RAB3C

RAB3C
Identifiers
Aliases	RAB3C, member RAS oncogene family
External IDs	OMIM: 612829 MGI: 1914545 HomoloGene: 23420 GeneCards: RAB3C
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	58,859,394 bp[1]
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)[2]
End	110,280,996 bp[2]
Gene ontology
Molecular function	• nucleotide binding; • GTP binding; • myosin V binding; • GO:0001948 protein binding; • GTP-dependent protein binding; • GTPase activity;
Cellular component	• perinuclear region of cytoplasm; • vesicle; • cytosol; • cell membrane; • membrane; • synaptic vesicle; • anchored component of synaptic vesicle membrane; • endosome;
Biological process	• regulation of exocytosis; • protein transport; • antigen processing and presentation; • intracellular protein transport; • vesicle docking involved in exocytosis; • protein secretion; • Rab protein signal transduction; • protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	115827
	67295
	ENSG00000152932
	ENSMUSG00000021700
	Q96E17
	P62823
	NM_138453; NM_001317915
	NM_023852; NM_001360099
	NP_001304844; NP_612462
	NP_076341; NP_001347028
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene.[5][6]

Interactions

Rab3C has been show to interact with ZWINT.[7]

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gollark: How common are they in the general populace?

gollark: I'm not sure I care very much about this fact, and it implies that the next ones will be similarly uninteresting.

gollark: <:Tohnk:445016844223381526>: an emoji which exists, or something more dangerous?

GRCh38: Ensembl release 89: ENSG00000152932 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000021700 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Cheng H, Ma Y, Ni X, Jiang M, Luo Y, Ying K, Xie Y, Ma Y (Aug 2002). "Cloning, mapping, and characterization of the human Rab3C gene". Biochemical Genetics. 40 (7–8): 263–72. doi:10.1023/A:1019834901190. PMID 12296628.
"Entrez Gene: RAB3C RAB3C, member RAS oncogene family".
van Vlijmen T, Vleugel M, Evers M, Mohammed S, Wulf PS, Heck AJ, Hoogenraad CC, van der Sluijs P (Aug 2008). "A unique residue in rab3c determines the interaction with novel binding protein Zwint-1". FEBS Letters. 582 (19): 2838–42. doi:10.1016/j.febslet.2008.07.012. PMID 18625232.

Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S (Jun 2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells". Proceedings of the National Academy of Sciences of the United States of America. 101 (22): 8313–8. doi:10.1073/pnas.0306709101. PMC 420391. PMID 15159548.
Fukuda M (Apr 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Schlüter OM, Khvotchev M, Jahn R, Südhof TC (Oct 2002). "Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion". The Journal of Biological Chemistry. 277 (43): 40919–29. doi:10.1074/jbc.M203704200. PMID 12167638.
Uphues I, Chern Y, Eckel J (Dec 1995). "Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats". FEBS Letters. 377 (2): 109–12. doi:10.1016/0014-5793(95)01315-6. PMID 8543030.

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