Prothionamide

Prothionamide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J04AD01 (WHO) ;
Identifiers
	IUPAC name 2-propylpyridine-4-carbothioamide;
CAS Number	14222-60-7 ;
PubChem CID	666418;
ChemSpider	579891 ;
UNII	76YOO33643;
CompTox Dashboard (EPA)	DTXSID7045940 ;
ECHA InfoCard	100.034.615
Chemical and physical data
Formula	C9H12N2S
Molar mass	180.27 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCc1cc(ccn1)C(=S)N;
	InChI InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) ; Key:VRDIULHPQTYCLN-UHFFFAOYSA-N ;
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Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis.[1]

It has also been tested for use in the treatment of leprosy.[2]

References

Wang F, Langley R, Gulten G, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. PMID 16525107.

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