OSM-9

OSM-9 also known as OSMotic avoidance abnormal family member 9 is a protein which in the nematode worm C. elegans is encoded by the osm-9 gene.[1]

OSMotic avoidance abnormal family member (osm-9) (Caenorhabditis elegans)
Identifiers
SymbolOSM-9
NCBI gene177117

Function

The OSM-9 protein is required for some olfactory and osmotic stimuli as well as a mechanosensory response to nose touch. This protein encodes a protein with ankyrin repeats and is closely related in sequence to the mammalian TRPV ion channels.[1] OSM-9 controls the biosynthesis of serotonin via regulation of the expression of the enzyme tryptophan hydroxylase.[2]

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gollark: ++supported_langs q
gollark: ++exec```pythonimport esolangs_discordprint(esolangs_discord.get_roles())```
gollark: <@346637662507237381>
gollark: 𝑨𝒍𝒍 π’‰π’‚π’Šπ’ 𝒕𝒉𝒆 π‘Όπ’π’Šπ’„π’π’…π’† π‘ͺπ’π’π’”π’π’“π’•π’Šπ’–π’Ž.

References
  1. Colbert HA, Smith TL, Bargmann CI (November 1997). "OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans". J. Neurosci. 17 (21): 8259–69. doi:10.1523/JNEUROSCI.17-21-08259.1997. PMC 6573730. PMID 9334401.
  2. Zhang S, Sokolchik I, Blanco G, Sze JY (April 2004). "Caenorhabditis elegans TRPV ion channel regulates 5HT biosynthesis in chemosensory neurons". Development. 131 (7): 1629–38. doi:10.1242/dev.01047. PMID 14998926.

Further reading


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