NicOx

Nicox SA (Euronext: COX) is an ophthalmology company developing treatments to maintain vision and improve occular health.[1] Nicox is headquartered in Sophia Antipolis, France, and its Chairman and CEO is Michele Garufi.[2][3]

NicOx S.A.
Société Anonyme
Traded asEuronext: COX
ISINFR0013018124 
Industrypharmaceutical industry 
Founded1996 (1996)
Headquarters,
Websitewww.nicox.com

Nicox is listed on Euronext Paris[4] (Compartment B: Mid Caps; Ticker symbol: COX) and is part of the CAC Healthcare, CAC Pharma & Bio and Next 150 indexes. Its pipeline includes three programs in development and it has two U.S. Food and Drug Administration (FDA) approved products.[5]

Pipeline

Nicox's lead program in clinical development is NCX 470, a novel, second-generation nitric oxide-donating bimatoprost analog, for lowering intraocular pressure (IOP) in patients with glaucoma.[6] NCX 470 is designed to release both bimatoprost, which is marketed under the brand name LUMIGAN, and nitric oxide following instillation into the eye. Bimatoprost is a prostaglandin analog, the most widely used class of drugs for IOP lowering in patients with open angle glaucoma and ocular hypertension.[7][8]

The company is also developing NCX 4251, a proprietary formulation of fluticasone, for acute exacerbations of blepharitis.[9] Nicox generates revenue from VYZULTA(R) in glaucoma and ZERVIATE(TM), or cetirizine ophthalmic solution, in allergic conjunctivitis. It has ongoing partnerships with Bausch & Lomb, Eyevance Pharmaceuticals and Ocumension Therapeutics.[10][11]

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References

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