Neisseria sigma-E sRNA
Neisseria sigma-E sRNA (NSE sRNA) is a non-coding RNA found in the bacterial genus Neisseria, including the two pathogens N. meningitidis and N. gonorrhoeae. The RNA was discovered in a screen for genes differentiated by high expression of the Sigma factor, sigma E.[1] Seven genes were predicted to be regulated by NSE sRNA, including fur, nadC and a putative TetR family transcriptional regulator, through base-pairing interactions with the 5' UTR. The sRNA transcript is terminated by a rho independent terminator.
Neisseria sigma-E sRNA | |
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A representation of the Neisseria sigma-E sRNA secondary structure including a colour scheme that indicates the degree of sequence conservation. | |
Identifiers | |
Symbol | NSE_sRNA |
Rfam | RF02270 |
Other data | |
RNA type | Gene |
Domain(s) | Bacteria; |
PDB structures | PDBe |
See also:
- NrrF sRNA
- Neisseria RNA thermometers
- Neisseria sibling sRNAs NmsR/RcoF
References
- Huis in 't Veld RA, Willemsen AM, van Kampen AH, Bradley EJ, Baas F, Pannekoek Y, van der Ende A (2011). Yang P (ed.). "Deep sequencing whole transcriptome exploration of the σE regulon in Neisseria meningitidis". PLOS ONE. 6 (12): e29002. doi:10.1371/journal.pone.0029002. PMC 3240639. PMID 22194974.
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