Nanoscopic scale

The nanoscopic scale (or nanoscale) usually refers to structures with a length scale applicable to nanotechnology, usually cited as 1–100 nanometers.[1] A nanometer is a billionth of a meter. The nanoscopic scale is (roughly speaking) a lower bound to the mesoscopic scale for most solids.

"Nanoscale" redirects here. For other uses, see Nanoscale (disambiguation).
A ribosome is a biological machine that utilizes nanoscale protein dynamics
A comparison of the scales of various biological and technological objects.

For technical purposes, the nanoscopic scale is the size at which fluctuations in the averaged properties (due to the motion and behavior of individual particles) begin to have a significant effect (often a few percent) on the behavior of a system, and must be taken into account in its analysis.

The nanoscopic scale is sometimes marked as the point where the properties of a material change; above this point, the properties of a material are caused by 'bulk' or 'volume' effects, namely which atoms are present, how they are bonded, and in what ratios. Below this point, the properties of a material change, and while the type of atoms present and their relative orientations are still important, 'surface area effects' (also referred to as quantum effects) become more apparent – these effects are due to the geometry of the material (how thick it is, how wide it is, etc.), which, at these low dimensions, can have a drastic effect on quantized states, and thus the properties of a material.

On October 8, 2014, the Nobel Prize in Chemistry was awarded to Eric Betzig, William Moerner and Stefan Hell for "the development of super-resolved fluorescence microscopy", which brings "optical microscopy into the nanodimension".[2][3][4]

Nanoscale machines
Some biological molecular machines

The most complex nanoscale molecular machines are proteins found within cells, often in the form of multi-protein complexes.[5] Some biological machines are motor proteins, such as myosin, which is responsible for muscle contraction, kinesin, which moves cargo inside cells away from the nucleus along microtubules, and dynein, which moves cargo inside cells towards the nucleus and produces the axonemal beating of motile cilia and flagella. "In effect, the [motile cilium] is a nanomachine composed of perhaps over 600 proteins in molecular complexes, many of which also function independently as nanomachines."[6] "Flexible linkers allow the mobile protein domains connected by them to recruit their binding partners and induce long-range allostery via protein domain dynamics."[6] Other biological machines are responsible for energy production, for example ATP synthase which harnesses energy from proton gradients across membranes to drive a turbine-like motion used to synthesise ATP, the energy currency of a cell.[7] Still other machines are responsible for gene expression, including DNA polymerases for replicating DNA, RNA polymerases for producing mRNA, the spliceosome for removing introns, and the ribosome for synthesising proteins. These machines and their nanoscale dynamics are far more complex than any molecular machines that have yet been artificially constructed.[8]

gollark: This cannot* go wrong.
gollark: Instead of having eaten pizza, I simply didn't, in all cases.
gollark: Why? Not eating pizza is basically the default option.
gollark: I don't even *eat* pizza.
gollark: This is NOT true. I have not in any way been sponsored by pizza companies. There have been no advertising agreements whatsoever with any companies producing pizza or otherwise to have me subliminally advertise pizza, as my profile picture is not a pizza. Since it is not a pizza, this is obviously not pizza advertisement whatsoever. No monetary exchanges or otherwise have occurred with companies engaged in pizza production for any reason relating to my profile picture. You are clearly engaged in libel and attempting to discredit my non-pizza-advertising status. It is IN NO WAY subliminal pizza advertising because I DO NOT work for pizza companies in any form. It's not pizza. There were no deals, under-the-table or otherwise, with pizza companies. No pizza companies pay for any kind of subliminal advertising involving me. People make that mistake, but I am not working for pizza companies doing subliminal advertising; that is not in any way what I am doing. I am NOT being sponsored by ANY pizza companies to display subliminal pizza advertising OF ANY KIND. Pizza companies have NO AFFILIATION with me in ANY FORM.

See also

References
  1. Hornyak, Gabor L. (2009). Fundamentals of Nanotechnology. Boca Raton, Florida: Taylor & Francis Group.
  2. Ritter, Karl; Rising, Malin (October 8, 2014). "2 Americans, 1 German win chemistry Nobel". AP News. Retrieved October 8, 2014.
  3. Chang, Kenneth (October 8, 2014). "2 Americans and a German Are Awarded Nobel Prize in Chemistry". New York Times. Retrieved October 8, 2014.
  4. Rincon, Paul (8 October 2014). "Microscope work wins Nobel Prize in Chemistry". BBC News. Retrieved November 3, 2014.
  5. Donald, Voet (2011). Biochemistry. Voet, Judith G. (4th ed.). Hoboken, NJ: John Wiley & Sons. ISBN 9780470570951. OCLC 690489261.
  6. Satir, Peter; Søren T. Christensen (2008-03-26). "Structure and function of mammalian cilia". Histochemistry and Cell Biology. 129 (6): 687–93. doi:10.1007/s00418-008-0416-9. PMC 2386530. PMID 18365235. 1432-119X.
  7. Kinbara, Kazushi; Aida, Takuzo (2005-04-01). "Toward Intelligent Molecular Machines: Directed Motions of Biological and Artificial Molecules and Assemblies". Chemical Reviews. 105 (4): 1377–1400. doi:10.1021/cr030071r. ISSN 0009-2665. PMID 15826015.
  8. Bu Z, Callaway DJ (2011). "Proteins MOVE! Protein dynamics and long-range allostery in cell signaling". Protein Structure and Diseases. Advances in Protein Chemistry and Structural Biology. 83. pp. 163–221. doi:10.1016/B978-0-12-381262-9.00005-7. ISBN 9780123812629. PMID 21570668.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.