Methyl hydroxychalcone

Methyl hydroxychalcone is a chalconoid found in cinnamon. It was thought to be an insulin mimetic, improving insulin response of diabetics.[1] It has since been determined that a flavonoid (cinnamtannin B1) is responsible for the insulin-like biological activity.[2]

Methyl hydroxychalcone
Names
IUPAC name
(E)-3-(3-hydroxyphenyl)-1-(3-methylphenyl)prop-2-en-1-one
Other names
MCHP
3'-Methyl-3-hydroxychalcone
Identifiers
3D model (JSmol)
ChemSpider
Properties
C16H14O2
Molar mass 238.28 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

References

  1. Karalee J. Jarvill-Taylor, PhD; Richard A. Anderson, PhD; Donald J. Graves, PhD (August 1, 2001). "A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes". J Am Coll Nutr. 20 (4): 327–36. PMID 11506060. Archived from the original on 2004-08-11. Retrieved 2014-02-27.
  2. Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014.



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