Leptospira alstoni

Leptospira alstoni is a gram negative, mobile, spirochete.[1] It is flexible, helical, and motile by means of two periplasmic flagella (axial fibrils). It is obligately aerobic and oxidase positive. It was named after J. M. Alston, a British microbiologist who made significant contributions to the study of Leptospirosis.[2] It is one of nine human or animal pathogenic species of Leptospira.[3] It was originally isolated from material submitted to the Veterinary Diagnostic Laboratory at Iowa State University during an outbreak of swine abortion in 1983.[4] It has been isolated and stored in liquid nitrogen or Ellinghausen-McCullough-Johnson-Harris medium.[5] It also has been isolated in China from a frog. The strain is also available from culture collections of the WHO collaborating centers. Lipase is not produced by this species. NaCl is not required for growth. Growth is inhibited by 8-azaguanine at 225 µg/mL or 2,6-diaminopurine (10 µg/mL) and copper sulfate. It contains serovars from the serogroup ranarum. DNA G+C content is 39±8 mol%.[2]

Leptospira alstoni
Scientific classification
Domain: Bacteria
Phylum: Spirochaetes
Order: Spirochaetales
Family: Leptospiraceae
Genus: Leptospira
Species:
L. alstoni
Binomial name
Leptospira alstoni

References
  1. Haake, D A; Champion, C I; Martinich, C; Shang, E S; Blanco, D R; Miller, J N; Lovett, M A (July 1993). "Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira spp". Journal of Bacteriology. 175 (13): 4225–4234. doi:10.1128/jb.175.13.4225-4234.1993. PMC 204853.
  2. Smythe, L.; Adler, B.; Hartskeerl, R. A.; Galloway, R. L.; Turenne, C. Y.; Levett, P. N. (14 September 2012). "Classification of Leptospira genomospecies 1, 3, 4 and 5 as Leptospira alstonii sp. nov., Leptospira vanthielii sp. nov., Leptospira terpstrae sp. nov. and Leptospira yanagawae sp. nov., respectively". International Journal of Systematic and Evolutionary Microbiology. 63 (Pt 5): 1859–1862. doi:10.1099/ijs.0.047324-0. PMID 22984140.
  3. Meny, Paulina; Menéndez, Clara; Quintero, Jair; Hernández, Elba; Ríos, Cristina; Balassiano, Ilana Teruszkin; Trindade, Camilla Nunes Dos Reis; Vital-Brazil, Juliana Magalhães; Ramos, Tatiane Mendes Varela; Ashfield, Natalia; Feble, Camila; Avila, Esthefani; Schelotto, Felipe; Varela, Gustavo (21 December 2017). "Characterization of Leptospira isolates from humans and the environment in Uruguay". Revista do Instituto de Medicina Tropical de São Paulo. 59: e79. doi:10.1590/s1678-9946201759079. PMC 5738764. PMID 29267587.
  4. Miller, David A.; Wilson, Mark A.; Owen, William J.; Beran, George W. (25 June 2016). "Porcine Leptospirosis in Iowa". Journal of Veterinary Diagnostic Investigation. 2 (3): 171–175. doi:10.1177/104063879000200303. PMID 2094443.
  5. Alexander, A. D., E. F. Lessel, L. B. Evans, E. Franck, and S. S. Green. 1972. Preservation of leptospiras by liquid-nitrogen refrigeration. Int. J. Syst. Bacteriol. 22:165-169.
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