Large cell neuroendocrine carcinoma of the lung

Large cell neuroendocrine carcinoma of the lung (LCNEC) is a highly malignant neoplasm arising from transformed epithelial cells originating in tissues within the pulmonary tree. It is currently considered to be a subtype of large cell lung carcinoma.

LCNEC is often generically grouped among the non-small cell lung carcinomas.[1]

Variants

The World Health Organization classification of lung tumors[1] recognizes a variant of LCNEC, namely "combined large cell neuroendocrine carcinoma" (c-LCNEC).

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References

Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; et al., eds. (2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). World Health Organization Classification of Tumours. Lyon: IARC Press. ISBN 978-92-832-2418-1. Archived from the original (PDF) on 23 August 2009. Retrieved 27 March 2010.

External links

Lung Cancer Home Page. The National Cancer Institute site containing further reading and resources about lung cancer.
. World Health Organization Histological Classification of Lung and Pleural Tumours. 4th Edition.

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[who2004-1] Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; et al., eds. (2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). World Health Organization Classification of Tumours. Lyon: IARC Press. ISBN 978-92-832-2418-1. Archived from the original (PDF) on 23 August 2009. Retrieved 27 March 2010.