Joseph DeSimone

Joseph M. DeSimone (born May 16, 1964) is an American chemist, inventor and entrepreneur, best known as the 2008 recipient of the $500,000 Lemelson–MIT Prize[2] and as the co-founder and CEO of Carbon, an American technology company.[3]

Joe DeSimone
DeSimone, 2008
Born (1964-05-16) May 16, 1964
NationalityUnited States
CitizenshipUnited States
Alma materUrsinus College, Virginia Polytechnic Institute and State University
AwardsHeinz Award in Technology, Economy & Employment (2017)
National Medal of Technology and Innovation (2013)
Kabiller Prize in Nanoscience and Nanomedicine (2015)
Lemelson–MIT Prize (2008)
AAAS Mentor Award (2010)
IRI Medal (2014)
Dickson Prize in Science (2014)
Scientific career
InstitutionsUniversity of North Carolina at Chapel Hill, North Carolina State University
ThesisSynthesis of well-defined single and multiphase polymers using various living polymerization methods (1990)
Doctoral advisorJames E. McGrath
Notable studentsAndrew Ian Cooper (postdoc)[1]

He is the Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and William R. Kenan Jr. Distinguished Professor of Chemical Engineering at North Carolina State University. DeSimone is also an adjunct member at Memorial Sloan-Kettering Cancer Center.[4]

DeSimone has published over 350 scientific articles and has over 200 issued patents in his name with over 200 patents pending.

Education

Joseph DeSimone received his BS in Chemistry in 1986 from Ursinus College in Collegeville, Pennsylvania and his Ph.D. in Chemistry in 1990 from Virginia Tech in Blacksburg, Virginia.[5][6]

Career

DeSimone is a member of the National Academy of Medicine (2014),[7] National Academy of Sciences (2012),[8] and the National Academy of Engineering (2005).[9] He is also a member of the American Academy of Arts and Sciences (2005).[10]

External video
Joseph DeSimone: What if 3D printing was 100x faster?, TED Talks

In the 1990s he developed an environmentally friendly manufacturing process that relies on supercritical carbon dioxide instead of water and bio-persistent surfactants for the creation of fluoropolymers or high-performance plastics, such as Teflon. In 2002 DeSimone, along with Dr. Richard Stack, a cardiologist at Duke University, co-founded Bioabsorbable Vascular Solutions (BVS) to commercialize a fully bioabsorbable, drug-eluting stent. BVS was acquired by Guidant in 2003. The technology is now marketed by Abbott Vascular for the treatment of coronary artery disease.

In recent years DeSimone’s academic research group has been heavily focused on learning how to bring the precision, uniformity and mass production techniques associated with the fabrication of nanoscale features found in the microelectronics industry to the nanomedicine field for the fabrication and delivery of vaccines and therapeutics for the treatment and prevention of diseases. Developed in the DeSimone laboratory, the PRINT technology (Particle Replication in Non-Wetting Templates) is central to the group's work.

DeSimone’s academic laboratory and the PRINT technology became a foundation for the Carolina Center for Cancer Nanotechnology Excellence funded by the National Cancer Institute.[11] DeSimone also co-founded Liquidia Technologies in 2004 based on PRINT.

Currently, DeSimone is on sabbatical leave from the University of North Carolina and is the co-founder and CEO of American technology company and manufacturer, Carbon, which develops printers with the Continuous Liquid Interface Production (CLIP) technology.[12]

Awards and honors

DeSimone was awarded the National Medal of Technology and Innovation, the highest honor in the U.S. for achievements related to technological progress, by President Barack Obama at the White House in May 2016.[13] In 2017, Dr. DeSimone received the 22nd Annual Heinz Award in Technology, the Economy, and Employment.

He is also the recipient of the 2015 Kabiller Prize in Nanoscience and Nanomedicine;[14] the 2014 IRI Medal; the 2014 Dickson Prize in Science; the 2014 American Chemical Society Kathryn C. Hach Award for Entrepreneurial Success;[15] the 2012 Walston Chubb Award for Innovation, presented by Sigma Xi, The Scientific Research Society, to honor and promote creativity in science and engineering;[16] the 2010 AAAS Mentor Award in recognition of his efforts to advance diversity in the chemistry PhD workforce;[17] the 2009 NIH Director's Pioneer Award;[18] the 2009 North Carolina Award, the highest honor the State of North Carolina can bestow to recognize notable achievements of North Carolinians in the fields of Literature, Science, the Fine Arts and Public Service; the 2008 Tar Heel of the Year by the Raleigh News & Observer; the 2007 Collaboration Success Award from the Council for Chemical Research; the 2005 American Chemical Society Award for Creative Invention; the 2002 John Scott Award presented by the Board of Directors of City Trusts, Philadelphia, given to "the most deserving" men and women whose inventions have contributed in some outstanding way to the "comfort, welfare and happiness" of mankind;[19] the 2002 Engineering Excellence Award by DuPont; the 2002 Wallace H. Carothers Award from the Delaware Section of the American Chemical Society; and the 2000 Oliver Max Gardner Award from the University of North Carolina. In 2019, DeSimone received the Wilhelm Exner Medal in Polymer Manufacturing.[20]

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References
  1. DeSimone, J. M.; Cooper, A. I.; Londono, J. D.; Wignall, G.; McClain, J. B.; Samulski, E. T.; Lin, J. S.; Dobrynin, A.; Rubinstein, M.; Burke, A. L. C.; Fréchet, J. M. J. (1997). "Extraction of a hydrophilic compound from water into liquid CO₂ using dendritic surfactants". Nature. 389 (6649): 368–371. Bibcode:1997Natur.389..368C. doi:10.1038/38706.
  2. Winners' Circle: Joseph M. DeSimone
  3. Joseph DeSimone at TED
  4. Memorial Sloan-Kettering Cancer Center Archived 2011-09-02 at the Wayback Machine
  5. "DeSimone Research Group: People: DeSimone". Archived from the original on 2013-03-13. Retrieved 2010-05-12.
  6. "UNC Faculty: DeSimone". Archived from the original on 2015-05-10. Retrieved 2009-01-03.
  7. Institute of Medicine Elects 70 New Members, 10 Foreign Associates (October 20, 2014) Archived February 14, 2015, at the Wayback Machine
  8. National Academy of Sciences Members and Foreign Associates Elected (May 1, 2012)
  9. "NAE Members Directory – Dr. Joseph M. DeSimone". U.S. National Academy of Engineering. Retrieved September 16, 2011.
  10. "Book of Members, 1780–2010: Chapter D" (PDF). American Academy of Arts and Sciences. Retrieved September 16, 2011.
  11. "Carolina Center of Nanotechnology Excellence". Carolina Center of Nanotechnology Excellence. Retrieved September 16, 2011.
  12. UNC-Chapel Hill researchers collaborate to develop revolutionary 3D printing technology
  13. Ray Gronberg (2016-05-19). "Chemist DeSimone feted at White House". The Herald-Sun (Durham, North Carolina). Retrieved 2016-05-25.
  14. Joseph DeSimone Receives $250,000 Kabiller Prize in Nanoscience and Nanomedicine
  15. Kathryn C. Hach Award For Entrepreneurial Success (3 March 2014)
  16. Joseph DeSimone, 2012 Walston Chubb Award for Innovation
  17. 2010 AAAS Mentor Award Goes to Joseph M. DeSimone of the University of North Carolina at Chapel Hill and North Carolina State University (16 February 2011)
  18. "2009 Pioneer Award Recipients". NIH Director's Pioneer Award Program. National Institutes of Health. Retrieved September 16, 2011.
  19. "John Scott Award Recipients". John Scott Award Advisory Committee. Archived from the original on July 1, 2010. Retrieved March 25, 2011.
  20. Bringing the Digital Revolution to Polymer Manufacturing, retrieved: 11. Sep. 2019 in Wilhelmexner.org.
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