Ilepcimide
Ilepcimide, also known as antiepilepserine, is an anticonvulsant.[1] It is a piperidine derivative that was first synthesized by Chinese researchers as an analogue of piperine, the main alkaloid and phytochemical of black pepper (and of other plants in the family Piperaceae).
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Formula | C15H17NO3 |
Molar mass | 259.305 g·mol−1 |
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Ilepcimide has serotonergic activity.[1][2][3]
See also
References
- C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. p. 1116. ISBN 978-0-412-46630-4. Retrieved 30 November 2012.
- Liu, G.Q., Algeria, S., Ceci, A., Gerattini, S., Gobi, M. and Murai, S. (1984). "Stimulation of serotonin synthesis in rat brain after antiepilepserine, an antiepileptic piperine derivative". Biochemical Pharmacology. 33: 3883–3886. doi:10.1016/0006-2952(84)90055-8.CS1 maint: multiple names: authors list (link)
- Yan, Q.S., Mishra, P.K., Burger, R.L., Bettendorf, A.F., Jobe, P.C. and Dailey J.W. (1992). "Evidence that carbamazepine and antiepilepserine may produce a component of their anticonvulsant effects by activating serotonergic neurons in genetically epilepsy-prone rats". J. Pharmacol. Exp. Ther. 261 (2): 652–659.CS1 maint: multiple names: authors list (link)
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