Hydrangeic acid

Hydrangeic acid is a stilbenoid found in the leaves of Hydrangea macrophylla.[1]

Hydrangeic acid

Names
IUPAC name 2-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]benzoic acid
Identifiers
3D model (JSmol)	Interactive image
ChemSpider	4476740
PubChem CID	5318116
InChI InChI=1S/C15H12O4/c16-12-8-5-10(6-9-12)4-7-11-2-1-3-13(17)14(11)15(18)19/h1-9,16-17H,(H,18,19)/b7-4+ Key: UWXXIBUTKVUHTR-QPJJXVBHSA-N InChI=1/C15H12O4/c16-12-8-5-10(6-9-12)4-7-11-2-1-3-13(17)14(11)15(18)19/h1-9,16-17H,(H,18,19)/b7-4+ Key: UWXXIBUTKVUHTR-QPJJXVBHBH
SMILES Oc2ccc(cc2)\C=C\c(c1C(O)=O)cccc1O
Properties
Chemical formula	C15H12O4
Molar mass	256.257 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Hydrangeic acid is being investigated as a possible antidiabetic drug as it significantly lowered blood glucose, triglyceride and free fatty acid levels in laboratory animals.[1]

See also

• Lunularic acid, the corresponding dihydrostilbenoid also found in H. macrophylla

References

1. Hydrangeic acid from the processed leaves of Hydrangea macrophylla var. thunbergii as a new type of anti-diabetic compound. Hailong Zhang, Hisashi Matsuda, Chihiro Yamashita, Seikou Nakamura and Masayuki Yoshikawa, European Journal of Pharmacology, Volume 606, Issues 1–3, 15 March 2009, Pages 255–261, doi:10.1016/j.ejphar.2009.01.005