Glutarimide
Glutarimide is the organic compound with the formula (CH2)3(CO)2NH. It is a white solid. The compound forms upon dehydration of the amide of glutaric acid.[2]
Names | |
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IUPAC name
Piperidine-2,6-dione | |
Other names
2,6-Diketopiperidine | |
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ChemSpider | |
ECHA InfoCard | 100.013.038 |
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Properties | |
C5H7NO2 | |
Molar mass | 113.11 g/mol |
Melting point | 155-157 °C[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Glutarimide is sometimes called 2,6-piperidinedione. It is the core of a variety of drugs, including barbituric acid and cycloheximide, a potent inhibitor of protein synthesis.[3]
References
- Glutarimide - Sigma-Aldrich
- Paris, G.; Berlinguet, L.; Gaudry, R.; English, Jr., J.; Dayan, J. E. (1957). "Glutaric Acid and Glutarimide". Organic Syntheses. 37: 47. doi:10.15227/orgsyn.037.0047.
- Hugh D. Sisler, Malcolm R. Siegel; Cycloheximide and Other Glutarimide Antibiotics; Mechanism of Action pp 283-307
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