Geoffrey Bodenhausen

Geoffrey Bodenhausen (born 1951) is a French chemist specializing in nuclear magnetic resonance, being highly cited in his field.[2] He is a Corresponding member of the Royal Netherlands Academy of Arts and Sciences and a Fellow of the American Physical Society.[3] He is professeur émérite at the Department of Chemistry at the École Normale Supérieure (ENS) in Paris and professeur honoraire at the Laboratory of Biomolecular Magnetic Resonance of the École Polytechnique Fédérale de Lausanne (EPFL). He is a member of the editorial board of the journal Progress in Nuclear Magnetic Resonance Spectroscopy.[4]. He is the chair of the editorial board of the journal Magnetic Resonance.

Geoffrey Bodenhausen
Geoffrey Bodenhausen in 2009
Born (1951-05-07) 7 May 1951
The Hague, Netherlands
NationalityFrench
Alma materUniversity of Oxford
Known forHSQC
Scientific career
Fieldschemistry, spectroscopy
InstitutionsÉcole Polytechnique Fédérale de Lausanne, École Normale Supérieure of Paris
Doctoral advisorRay Freeman
Doctoral studentsLyndon Emsley (1991)[1]

Education

He received a Diploma in chemistry from ETH Zurich in 1974, and a D.Phil. from Oxford University in 1977, supervised by Ray Freeman.

Career

Bodenhausen began his post-doctoral research under the supervision of Robert and Regitze Vold at the University of California in San Diego. He subsequently worked with Leo Neuringer and Robert G. Griffin at the Massachusetts Institute of Technology and then in 1980 he moved to the ETH in Zurich, where he joined the group of Richard R. Ernst.

In 1985 he was appointed to a professorship at the University of Lausanne. In 1994 he became a professor at the Florida State University in Tallahassee filling the position of Director of the Institute for Advanced Studies in Magnetic Resonance.[5] In 1996 he was elected fellow of the American Physical Society "for his numerous contributions toward making magnetic resonance one of the most sophisticated and versatile methods available for gaining insight into structure and dynamics of molecules in condensed and gas phase."[3]

In 1996 he was awarded a professorship at the Ecole Normale Supérieure in Paris. He also held a part-time position at the École Polytechnique Fédérale de Lausanne.

From 2005 to 2011 he chaired the Board of Trustees of EUROMAR.[6][7]

Research

Bodenhausen was one of the pioneers in the field of two-dimensional Fourier transform NMR spectroscopy. In the group of Ray Freeman he contributed to some of the first heteronuclear experiments.[8]

In 1976 he proposed a scheme to induce selective excitation of small portions of multiline spectra, later named DANTE by Morris and Freeman.[9]

In 1977 Bodenhausen and Freeman showed how it was possible by observing spectrum of a heteronucleus (an atomic nucleus other than a proton) to achieve indirect detection of the proton resonance frequencies, and the correlations of chemical shifts between protons and heteronuclei.[10][11] In 1980 Bodenhausen and D. J. Ruben introduced the HSQC (Heteronuclear Single Quantum Coherence) experiment, which produces two-dimensional (2D) spectra with one axis for protons (1H) and the other for a heteronucleus, usually 13C or 15N.[12][13] This double INEPT has been the base for many subsequent heteronuclear single quantum experiments published in the literature[14] and it has proven pivotal in the spectroscopy organic chemistry and in the field of protein NMR.

One of the first steps in increasing the information content of NMR spectra was the introduction of a relayed homonuclear coherence transfer by Geoffrey Bodenhausen together with Gerhard Eich.[15]

In 1984 he published with Herbert Kogler and Richard R. Ernst a pivotal article in Journal of Magnetic Resonance where they described how to design phase cycles allowing the selection of specific coherence-transfer pathways in NMR pulse experiment.[16]

In 1987 he published with Richard R. Ernst and Alexander Wokaun Principles of Nuclear Magnetic Resonance in One and Two Dimensions, considered a classical monograph on the topic of multidimensional NMR.[17]

Honours and awards

Books
  • Bodenhausen, Geoffrey; Wokaun, Alexander (1987). Principles of Nuclear Magnetic Resonance in One and Two Dimension. Clarendon Press. p. 690. ISBN 9780198556473.

Patents
  • DE Patent 3839820, Lyndon Emsley & Geoffrey Bodenhausen, "Verfahren zum selektiven Anregen von nmr-Signalen", issued May 31, 1990
  • DE Patent 3940633, Lyndon Emsley & Geoffrey Bodenhausen, "Gauss-Impuls-Kaskade", issued June 13, 1991
  • US Patent 5327086, Geoffrey Bodenhausen; Jean-Marc Boehelen & Irene Burghardt, "Multiple-quantum NMR with frequency-modulated chirp pulses", issued July 5, 1994
  • US Patent 2009039883, Geoffrey Bodenhausen; Paul Vasos & Riddhiman Sarkar, "Singlet-state exchange NMR spectroscopy for the study of very slow dynamic proceses", issued February 12, 2009
  • US Patent 2012286782, Sami Jannin; Aurelien Bornet & Geoffrey Bodenhausen, "Method for NMR spectroscopy with sustained induction decays of long-lived coherences", issued November 15, 2012
  • US Patent 2013021031, Diego Carnvale & Geoffrey Bodenhausen, "Fourier Tickling For Homonuclear Decoupling in NMR"
  • EP Patent 2786165, Geoffrey Bodenhausen; Aurelien Bornet & Nicola Salvi et al., "Method for the NMR based determination of the affinity of drugs for a target protein", issued December 8, 2014
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References
  1. "MÉDAILLES D'ARGENT 2005" (PDF) (in French). Centre national de la recherche scientifique. 9 October 2010. pp. 20–21. Archived from the original (PDF) on 9 July 2012. Retrieved 2015-10-29. Cite magazine requires |magazine= (help)
  2. "Geoffrey Bodenhausen". Retrieved June 13, 2017.
  3. "APS Fellow Archive".
  4. Progress in Nuclear Magnetic Resonance Spectroscopy Editorial Board. Retrieved 3 May 2016.
  5. "REPORT of the NHMFL USERS' COMMITTEE MEETING of SEPTEMBER 29-30, 1994 at FLORIDA STATE UNIVERSITY". 1994. Retrieved 12 March 2016. We are also pleased to see that the position of Director of the Institute for Advanced Studies in Magnetic Resonance has been successfully filled by Geoffrey Bodenhausen. Now that a director is in place, we urge the NMR group to present a plan defining the NMR user facility, including the infrastructure, contact personnel and user support.
  6. http://www.euromar.org, ed. (2015). "Euromar Board of Trustees – Fall 2015" (PDF). Retrieved 14 January 2016.
  7. Office, Research (2008-12-31). Ecole Polytechnique Fédérale de Lausanne (ed.). "Prof. Geoffrey Bodenhausen - Chair of the Board of Trustees EUROMAR". Retrieved 10 March 2016. Cite journal requires |journal= (help)
  8. http://www.nobelprize.org/, ed. (1991). "Richard R. Ernst - Biographical". Retrieved 1 May 2016.
  9. E. Fukushima, S:B:W: Roeder, Experimental Pulse NMR, II.D.2. Selective excitations, pag. 114-115
  10. G. Bodenhausen, R. Freeman: J. Magn. Reson. 28, 463 (1977)
  11. Slichter, Principles of Magnetic Resonance, p. 140
  12. Bodenhausen, G.; Ruben, D.J. (1980). "Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy" (PDF). Chemical Physics Letters. 69 (1): 185–189. Bibcode:1980CPL....69..185B. doi:10.1016/0009-2614(80)80041-8.
  13. Simpson, Jeffrey H. (2008). "Modern NMR Instrument Architecture". Organic Structure Determination Using 2-D NMR Spectroscopy. Elsevier. p. 33. ISBN 978-0-12-088522-0.
  14. Turner, Christopher J. (2011). "Heteronuclear Assignment Techniques". Encyclopedia of Magnetic Resonance. p. 5. doi:10.1002/9780470034590.emrstm0207.pub2. ISBN 978-0470034590.
  15. Grant, David M. (1996-06-03). Encyclopedia of Nuclear Magnetic Resonance, Historical Perspectives lyear=1996. p. 299. ISBN 9780471958390.
  16. Elsevier Journals, ed. (20 September 2001). Professor Geoffrey Bodenhausen on his landmark article in JMR. Retrieved 13 February 2016.
  17. Oleg N. Antzutkin, Chapter 7, Molecular Structure Determination: Applications in Biology, p. 281 in Melinda J. Duer, Solid-State NMR Spectroscopy Principles and Applications
  18. Swiss National Science Foundation (ed.). "National Latsis Prize - Prize winners since 1984". Retrieved 10 March 2016.
  19. NO SOURCE SO FAR; THAT'S WHY I DIDN'T INSERT IT YET
  20. "G. BODENHAUSEN". Retrieved 10 March 2016.
  21. J. Elguero, «El premio bilateral hispano-luso de la RSEQ llevará el nombre de Madinaveitia», Anales de Química, 2009, 105, 67-69.
  22. Office, Research (31 December 2008). Ecole Polytechnique Fédérale de Lausanne (ed.). "Prof. G. Bodenhausen - International Society for Magnetic Resonance". Retrieved 10 March 2016. Cite journal requires |journal= (help)
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