G cell

In anatomy, the G cell or gastrin cell, is a type of cell in the stomach and duodenum that secretes gastrin. It works in conjunction with gastric chief cells and parietal cells. G cells are found deep within the pyloric glands of the stomach antrum, and occasionally in the pancreas[1] and duodenum. The vagus nerve innervates the G cells. Gastrin-releasing peptide is released by the post-ganglionic fibers of the vagus nerve onto G cells during parasympathetic stimulation. The peptide hormone bombesin also stimulates gastrin from G cells. Gastrin-releasing peptide, as well as the presence of amino acids in the stomach, stimulates the release of gastrin from the G cells. Gastrin stimulates enterochromaffin-like cells to secrete histamine.[2] Gastrin also targets parietal cells by increasing the amount of histamine and the direct stimulation by gastrin, causing the parietal cells to increase HCl secretion in the stomach.

G cell
Control of stomach acid
Details
SystemDigestive system
LocationStomach and duodenum
FunctionGastrin secretion
Identifiers
Latinendocrinocytus G
THH3.04.02.0.00031
Anatomical terms of microanatomy

Structure
Micrograph of the gastric antrum showing abundant fried egg-like G cells. H&E stain.

G cells have a distinctive microscopic appearance that allows one to separate them from other cells in the gastric antrum; their nuclei are centrally located in the cell. They are found in the middle portion of the gastric glands.

gollark: Oh, you got it to UTTERLY work?
gollark: There's a nim→JS compiler.
gollark: It supports that.
gollark: I mean, I could write nim on the frontend too I guess?
gollark: I'll probably do it if I can work out how to append after things in J§.

See also

References
  1. "G cell", Medcyclopaedia, GE
  2. Guyton, Arthur C.; John E. Hall (2006). Textbook of Medical Physiology (11 ed.). Philadelphia: Elsevier Saunders. p. 797. ISBN 0-7216-0240-1.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.