Ethyl chloroformate
Ethyl chloroformate is the ethyl ester of chloroformic acid. It is a reagent used in organic synthesis for the introduction of the ethyl carbamate protecting group[2] and for the formation of carboxylic anhydrides.
Names | |
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Preferred IUPAC name
Ethyl carbonochloridate | |
Other names
Chloroformic acid ethyl ester Cathyl chloride Ethyl chlorocarbonate | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.007.981 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C3H5ClO2 | |
Molar mass | 108.52 g/mol |
Appearance | Clear liquid |
Density | 1.1403 g/cm3 |
Boiling point | 95 °C (203 °F; 368 K) |
Decomposes | |
Hazards | |
Main hazards | Corrosive Flammable |
NFPA 704 (fire diamond) | |
Flash point | 61 °C (142 °F; 334 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Safety
Ethyl chloroformate is a highly toxic substance. It causes severe burns when comes in contact with eyes and/or skin, can be fatal if swallowed or inhaled.[3]
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References
- Merck Index, 11th Edition, 3742.
- Protective Groups in Organic Synthesis, Third Edition, Theodora W. Greene and Peter G. M. Wuts, pages 504-506, ISBN 0-471-16019-9
- PubChem. "Ethyl chloroformate". pubchem.ncbi.nlm.nih.gov. Retrieved 2019-09-04.
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