Enterobacteria phage P4
Enterobacteria phage P4 (also known as satellite phage P4) is a temperate bacteriophage strain of species Escherichia virus P2 within genus Peduovirus (formerly P2-like viruses, P2virus, and P2likevirus), subfamily Peduovirinae, family Myoviridae.[1] It is a satellite virus, requiring P2-related helper phage to grow lytically.
Enterobacteria phage P4 | |
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Virus classification | |
(unranked): | Virus |
Realm: | Duplodnaviria |
Kingdom: | Heunggongvirae |
Phylum: | Uroviricota |
Class: | Caudoviricetes |
Order: | Caudovirales |
Family: | Myoviridae |
Genus: | Peduovirus |
Species: | Escherichia virus P2 |
Strain: | Enterobacteria phage P4 |
Structure
The P4 virion has a tail and an icosahedral head containing a linear double-stranded DNA genome of 11,627 kb.[2][3]
Life cycle
Phage P4 infects Escherichia coli. It is a satellite virus which cannot engage in lytic growth without the presence of a P2-related helper phage. It generally follows a lysogenic life cycle: after infection, the P4 genome integrates into that of its host. The P4 genome can also exist on its own within the host cell and can replicate as a free plasmid.[4]
References
- Pruss, G; Goldstein, RN; Calendar, R (June 1974). "In vitro packaging of satellite phage P4 DNA". Proceedings of the National Academy of Sciences of the United States of America. 71 (6): 2367–71. doi:10.1073/pnas.71.6.2367. PMC 388456. PMID 4526304.
- Briani, Federica; Dehò, Gianni; Forti, Francesca; Ghisotti, Daniela (2002). "The Plasmid Status of Satellite Bacteriophage P4". Plasmid. 45 (1): 1–17. doi:10.1006/plas.2000.1497. PMID 11319927.
- Claverie JM, Abergel C (2009). "Mimivirus and its Virophage". Annual Review of Genetics. 43: 49–66. doi:10.1146/annurev-genet-102108-134255. PMID 19653859.
- Christie, GE; Calendar, R (1990). "Interactions between satellite bacteriophage P4 and its helpers". Annual Review of Genetics. 24: 465–90. doi:10.1146/annurev.ge.24.120190.002341. PMID 2088176.