DES
Computing
- Data Encryption Standard, a broken block cipher
- DirectShow Editing Services, an Application Programming Interface
- Discrete event simulation, a kind of scientific modelling
Education
- Deccan Education Society, a private education institution based in Pune, India.
- Department of Education and Science (UK), the former name of the Department for Education and Skills
Medical
- Diethylstilbestrol, a synthetic estrogen and the origin of the phrase "DES daughter"
- DES gene, which encodes the desmin protein
- Diffuse esophageal spasm, a disorder of the esophagus
- Dissociative Experiences Scale, a questionnaire to screen for dissociative identity disorder
- Drug-eluting stent, a medical device
- Dry eye syndrome, also known as keratoconjunctivitis sicca
- Dysequilibrium syndrome, a congenital disorder of the nervous system
Other uses
- Dar es Salaam
- Dark Energy Survey, an astronomy project
- Deep Ecliptic Survey, an astronomy project
- Deep eutectic solvent, an ionic solvent
- Defence Equipment and Support, British MOD's defence procurement arm
- Delivered Ex Ship, an international sales term
- Detached eddy simulation, a model in fluid dynamics
- Desroches Airport, by IATA code
- Arizona Department of Economic Security, a US government organization providing a variety of social support services to Arizona residents
- Desmond (name), a male given name in shortened form
- Desiree (given name), a female given name in shortened form
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