DAZ associated protein 1

Function

In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ1 (Deleted in Azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes an RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.[4]

Interactions

DAZ associated protein 1 has been shown to interact with DAZ1.[5]

gollark: If you want to use the NLI model instead of a semantic search-y thing, you probably will have bad performance issues since it *does* actually have to compare all the input sentences against all the example sentences using a full pass through the model.
gollark: That just puts the tokenized tokens onto the GPU, not the model. I would expect that to just error, actually, if the model and tokens are on separate devices.
gollark: No, that thing is fine, but your *other* model is not being loaded onto the GPU.
gollark: https://www.sbert.net/examples/applications/semantic-search/README.html is kind of like what you want.
gollark: Instead of recomputing the embeddings every time a new sentence comes in.

References
  1. GRCh38: Ensembl release 89: ENSG00000071626 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Tsui S, Dai T, Roettger S, Schempp W, Salido EC, Yen PH (August 2000). "Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1". Genomics. 65 (3): 266–73. doi:10.1006/geno.2000.6169. PMID 10857750.
  4. "Entrez Gene: DAZAP1 DAZ associated protein 1".
  5. Tsui S, Dai T, Roettger S, Schempp W, Salido EC, Yen PH (May 2000). "Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1". Genomics. 65 (3): 266–73. doi:10.1006/geno.2000.6169. PMID 10857750.

Further reading


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