Cinchonidine

Cinchonidine is an alkaloid found in Cinchona officinalis and Gongronema latifolium.[2] It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonine.

Cinchonidine
Names
IUPAC name
(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol
Identifiers
3D model (JSmol)
89690
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.930
EC Number
  • 207-622-3
KEGG
UNII
Properties
C19H22N2O
Molar mass 294.43 g/mol
Density 1.2 g/mL
Melting point 204 to 205 °C (399 to 401 °F; 477 to 478 K)
Boiling point 464.5 °C (868.1 °F; 737.6 K)
slightly soluble 0,25 g·l−1 (20 °C) [1]
Hazards
GHS pictograms
GHS Signal word Warning
GHS hazard statements
H302, H317, H361, H373
P201, P202, P260, P261, P264, P270, P272, P280, P281, P301+312, P302+352, P308+313, P314, P321, P330, P333+313, P363, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. Herstellerangaben der Firma Merck, 5. Jan. 2008
  2. "NCATS Inxight: Drugs". drugs.ncats.io. Retrieved 2020-01-22.
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