Cetadiol
Cetadiol, also known as androst-5-ene-3β,16α-diol, is a drug described as a "steroid tranquilizer" which was briefly investigated as a treatment for alcoholism in the 1950s.[1][2][3][4][5] It is an androstane steroid and analogue of 5-androstenediol (androst-5-ene-3β,17β-diol) and 16α-hydroxy-DHEA (androst-5-ene-3β,16α-diol-17-one), but showed no androgenic or myotrophic activity in animal bioassays.[4] The drug was reported in 1956 and studied until 1958.[1]
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| Other names | Androst-5-ene-3β,16α-diol; 3β,16α-Dihydroxy-5-androstene |
| Routes of administration | Oral |
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| Formula | C19H30O2 |
| Molar mass | 290.447 g·mol−1 |
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Chemistry
gollark: ?tag bismuth1
gollark: ?tag blub
gollark: ?tag create blub Graham considers a hypothetical Blub programmer. When the programmer looks down the "power continuum", he considers the lower languages to be less powerful because they miss some feature that a Blub programmer is used to. But when he looks up, he fails to realise that he is looking up: he merely sees "weird languages" with unnecessary features and assumes they are equivalent in power, but with "other hairy stuff thrown in as well". When Graham considers the point of view of a programmer using a language higher than Blub, he describes that programmer as looking down on Blub and noting its "missing" features from the point of view of the higher language.
gollark: ?tag blub Graham considers a hypothetical Blub programmer. When the programmer looks down the "power continuum", he considers the lower languages to be less powerful because they miss some feature that a Blub programmer is used to. But when he looks up, he fails to realise that he is looking up: he merely sees "weird languages" with unnecessary features and assumes they are equivalent in power, but with "other hairy stuff thrown in as well". When Graham considers the point of view of a programmer using a language higher than Blub, he describes that programmer as looking down on Blub and noting its "missing" features from the point of view of the higher language.
gollark: > As long as our hypothetical Blub programmer is looking down the power continuum, he knows he's looking down. Languages less powerful than Blub are obviously less powerful, because they're missing some feature he's used to. But when our hypothetical Blub programmer looks in the other direction, up the power continuum, he doesn't realize he's looking up. What he sees are merely weird languages. He probably considers them about equivalent in power to Blub, but with all this other hairy stuff thrown in as well. Blub is good enough for him, because he thinks in Blub.
See also
- Androstadienol (androsta-5,16-dien-3β-ol)
- Androstenol (5α-androst-16-en-3α-ol)
- 4-Androstadienol (PH94B; Aloradine)
- Cyclopregnol
References
- J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 86–. ISBN 978-1-4757-2085-3.
- Martin Negwer; Hans-Georg Scharnow (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 1841. ISBN 978-3-527-30247-5.
- LEMERE F (1957). "New steroid hormone tranquilizing agent (cetadiol)". Am J Psychiatry. 113 (10): 930. doi:10.1176/ajp.113.10.930. PMID 13402989.
- CAMPBELL CH, SLEEPER HG (1956). "Cetadiol (5-androstene-3 16-diol) in the treatment of hospitalized alcoholics". Am J Psychiatry. 112 (10): 845. doi:10.1176/ajp.112.10.845. PMID 13302491.
- WEXLER D, LEIDERMAN PH, MENDELSON J, KUBZANSKY P, SOLOMON P (1958). "The effect of cetadiol on delirium tremens, alcoholic hallucinosis, and alcohol withdrawal". Am J Psychiatry. 114 (10): 935–6. doi:10.1176/ajp.114.10.935. PMID 13508929.
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