Carrelame

Carrelame is an extremely high potency artificial sweetener of the guanidine class, closely related to lugduname. While Carrelame is roughly 160,000x as sweet as sucrose, lugduname is still somewhat sweeter.[1] Like other members of this class, it has not been approved for use in food due to unknown long term toxicity, although it appears safe in pigs.[2]

Carrelame

Names
IUPAC name (Z)-N-{[(3,5-Dichlorophenyl)amino][(diphenylmethyl)amino]methylene}glycine
Identifiers
CAS Number	180045-74-3
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2220782
ChemSpider	26468003
PubChem CID	46841915
CompTox Dashboard (EPA)	DTXSID40676748
InChI InChI=1S/C22H19Cl2N3O2/c23-17-11-18(24)13-19(12-17)26-22(25-14-20(28)29)27-21(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,21H,14H2,(H,28,29)(H2,25,26,27) Key: QMIBAVZANYVPEF-UHFFFAOYSA-N InChI=1/C22H19Cl2N3O2/c23-17-11-18(24)13-19(12-17)26-22(25-14-20(28)29)27-21(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,21H,14H2,(H,28,29)(H2,25,26,27) Key: QMIBAVZANYVPEF-UHFFFAOYAI
SMILES c1ccc(cc1)C(c2ccccc2)N/C(=N/CC(=O)O)/Nc3cc(cc(c3)Cl)Cl
Properties
Chemical formula	C22H19Cl2N3O2
Molar mass	428.311
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

• Sucrononic acid

Additional reading

• "Alternative Sweeteners". Google Books. Retrieved 13 April 2020.
• "Low-calorie Sweeteners - Google Books". google.com. Retrieved 13 April 2020.
• "Optimising Sweet Taste in Foods - Google Books". google.com. Retrieved 13 April 2020.

References

1. Glaser D (2002), "Specialization and phyletic trends of sweetness reception in animals" (PDF), Pure Appl. Chem., 74 (7): 1153–1158, doi:10.1351/pac200274071153
2. Nofre, C; Glaser, D; Tinti, JM; Wanner, M (2002). "Gustatory responses of pigs to sixty compounds tasting sweet to humans". Journal of Animal Physiology and Animal Nutrition. 86 (3–4): 90–96. doi:10.1046/j.1439-0396.2002.00361.x. PMID 11972677.