CTTNBP2NL

CTTNBP2 N-terminal-like protein is a protein that in humans is encoded by the CTTNBP2NL gene.[5][6] It is a substrate for phosphorylation.[7]

CTTNBP2NL
Identifiers
Aliases	CTTNBP2NL, CTTNBP2 N-terminal like
External IDs	OMIM: 615100 MGI: 1933137 HomoloGene: 36371 GeneCards: CTTNBP2NL
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.2 Start 112,396,214 bp[1] End 112,463,456 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.2 Start 105,001,915 bp[2] End 105,053,146 bp[2]
Gene ontology Molecular function • protein phosphatase 2A binding • GO:0001948 protein binding Cellular component • cytoplasm • actin cytoskeleton • cytoskeleton Biological process • protein dephosphorylation • negative regulation of transporter activity • negative regulation of transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55917	80281
Ensembl	ENSG00000143079	ENSMUSG00000062127
UniProt	Q9P2B4	Q99LJ0
RefSeq (mRNA)	NM_018704	NM_001163332 NM_001163333 NM_030249
RefSeq (protein)	NP_061174	NP_001156804 NP_001156805 NP_084525
Location (UCSC)	Chr 1: 112.4 – 112.46 Mb	Chr 3: 105 – 105.05 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

CTTNBP2NL has been shown to interact with:

• FAM40A,[7] and
• MOBKL3,[7]
• PDCD10,[7]
• PPP2CA,[7]
• PPP2R1A,[7]
• RP6-213H19.1,[7]
• STK24,[7]
• STRN3,[7] and
• STRN.[7]

References

1. GRCh38: Ensembl release 89: ENSG00000143079 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000062127 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Feb 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
6. "Entrez Gene: CTTNBP2NL CTTNBP2 N-terminal like".
7. Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

External links

• Human CTTNBP2NL genome location and CTTNBP2NL gene details page in the UCSC Genome Browser.

Further reading

• Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (Oct 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.