Collagen, type XXVIII, alpha 1

COL28A1
Identifiers
Aliases	COL28A1, COL28, collagen type XXVIII alpha 1, collagen type XXVIII alpha 1 chain
External IDs	OMIM: 609996 MGI: 2685312 HomoloGene: 66345 GeneCards: COL28A1
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	7,535,873 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	8,192,617 bp[2]
Gene ontology
Molecular function	• peptidase inhibitor activity; • serine-type endopeptidase inhibitor activity; • extracellular matrix structural constituent; • extracellular matrix structural constituent conferring tensile strength;
Cellular component	• proteinaceous extracellular matrix; • extracellular region; • basement membrane; • collagen; • endoplasmic reticulum lumen; • extracellular matrix; • extracellular; • collagen-containing extracellular matrix;
Biological process	• negative regulation of peptidase activity; • cell adhesion; • negative regulation of endopeptidase activity; • extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	340267
	213945
	ENSG00000215018
	ENSMUSG00000068794
	Q2UY09
	Q2UY11
	NM_001037763
	NM_001037865
	NP_001032852
	NP_001032954
	Wikidata
View/Edit Human	View/Edit Mouse

Collagen, type XXVIII, alpha 1 also known as COL28A1 is a protein that in humans is encoded by the COL28A1 gene.[5] This protein belongs to a class of collagens that contain von Willebrand factor type A domains.[6] The protein is encoded by the COL28A1 gene which contains 45 exons and is found of the p arm of chromosome 7.[6]

References

GRCh38: Ensembl release 89: ENSG00000215018 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000068794 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Veit G, Kobbe B, Keene DR, Paulsson M, Koch M, Wagener R (Feb 2006). "Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain". The Journal of Biological Chemistry. 281 (6): 3494–504. doi:10.1074/jbc.M509333200. PMID 16330543.
"COL28A1 collagen, type XXVIII, alpha 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2015-09-25.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000215018 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068794 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16330543-5] Veit G, Kobbe B, Keene DR, Paulsson M, Koch M, Wagener R (Feb 2006). "Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain". The Journal of Biological Chemistry. 281 (6): 3494–504. doi:10.1074/jbc.M509333200. PMID 16330543.

[entrez-6] "COL28A1 collagen, type XXVIII, alpha 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2015-09-25.