Anthrax immune globulin

Anthrax immune globulin, tradename Anthrasil, is a human immune globulin that is used in combination with antibiotics to treat anthrax. It was developed by Cangene and purchased in 2011 by the Biomedical Advanced Research and Development Authority (BARDA) under Project Bioshield. On 24 March 2015 it was granted approval by the United States Food and Drug Administration for use in treating inhalation anthrax in conjunction with antibiotics.[1][2]

Anthrax immune globulin
Clinical data
Trade namesAnthrasil
Routes of
administration		Intravenous
Legal status
Legal status
Identifiers
ChemSpider
  • none

Preparation

Anthrax immune globulin is prepared from the plasma of donors who have been vaccinated against anthrax.

Safety and efficacy testing

Due to the ethical and feasibility concerns with testing the efficacy of anthrax immune globulin in humans, it was tested in rabbits and monkeys under the FDA's animal efficacy rule. Following efficacy testing, anthrax immune globulin was tested for safety in human volunteers, where the most common side effects were headache, back pain, nausea and infusion site pain and swelling.

gollark: I have the bulk download part done for reasons.
gollark: .
gollark: ABR would accept esobot messages if they didn't start with <jan Whatever>
gollark: It can process them differently internally.
gollark: The spec is totally compatible with floats with 0-bit exponents and no sign.

References
  1. "FDA approves treatment for inhalation anthrax". United States Food and Drug Administration. 25 March 2015.
  2. "Anthrasil Approval History". Drugs.com. Retrieved 26 March 2015.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.