Alison Butler
Alison Butler is a Distinguished Professor in the Department of Chemistry and Biochemistry at the University of California, Santa Barbara. She works on bioinorganic chemistry and metallobiochemistry. She is a Fellow of the American Association for the Advancement of Science (1997), American Chemical Society (2012), and the American Academy of Arts and Sciences (2019).
Alison Butler | |
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Alma mater | Reed College (B.A.) University of California, San Diego (Ph.D.) |
Scientific career | |
Institutions | University of California, Los Angeles California Institute of Technology University of California, Santa Barbara |
Doctoral advisors | Robert G. Linck Teddy G. Traylor |
Other academic advisors | Joan S. Valentine Harry B. Gray |
Early life and education
Butler was fascinated by magnetism as a child.[1] She studied at Reed College, graduating in 1977.[2] Her father was one of the first members of the biology faculty at University of California, San Diego.[3] She started in immunology, but moved into chemistry to work with transition metals.[3] She worked with Professor Tom Dunne on An intramolecular electron transfer study: the reduction of pyrazinepentaaminecobalt (III) by chromium (II).[2] She earned her PhD at University of California, San Diego in 1982 under Robert G. Linck and Teddy G. Traylor.[4] During her graduate studies, Butler read an article about metallo-enzymes in the New Yorker.[1]
Career
Butler worked as a postdoctoral fellow at University of California, Los Angeles with Joan S. Valentine and at California Institute of Technology with Harry B. Gray.[4] She was appointed to the faculty at University of California, Santa Barbara in 1986.[4] Here she was awarded an American Cancer Society Junior Faculty Research Award.[4] She was awarded the 34th University of California, Santa Barbara Harold J Plous Award.[5]
She looks to develop new siderophores, small molecules that bind iron in microorganisms.[6] She uses genomics to predict new siderophores, and bioinformatics to discover new siderophores . She explores how siderophores adhere to mica and look at how they can promote surface colonisation.[6] She identified that siderophores become sticky when wet, which may help to develop underwater adhesives.[1][7] Her current research considers the uptake of microbial iron, vanadium haloperoxidases in microbial quorum sensing and cryptic halogenation, bio-inspired wet adhesion using catechol compounds and the oxidative disassembly of lingnin.[6][8][9][10] Her research into the bioinorganic chemistry of iron is funded by the National Institutes of Health and National Science Foundation.[11][12] She studies how transition metal ions are used by marine organisms.[13]
In 2012 she became the President of the Society for Biological Inorganic Chemistry, and served until 2014.[14] She was made a Fellow of the American Chemical Society in July 2012.[15] She delivered the 2016 Douglas Eveleigh Endowed Lecture at the Waksman Institute of Microbiology.[16] In 2018 she was awarded the American Chemical Society Alfred Bader Award for her work on siderophores.[6][17] She was elected to the American Academy of Arts and Sciences in 2019.[18]
References
- Harrison Tasoff for UCSB. "Organic Prize for UCSB Inorganic Researcher Alison Butler". Retrieved 2018-10-11.
- alan (May 14, 2018). "Alison Butler '77 Receives ACS Bader Award in Bioinorganic Chemistry | Chemistry News". blogs.reed.edu. Retrieved 2018-10-11.
- "Research Profiles - Alison Butler". University of California Research. Retrieved 2018-10-11.
- "Alison Butler". www.chem.ucsb.edu. Retrieved 2018-10-08.
- "Members - Alison Butler". labs.chem.ucsb.edu. Retrieved 2018-10-08.
- Julie Cohen (September 18, 2017). "Ironing Out a Puzzle". The UCSB Current. Retrieved 2018-10-08.
- "Sticky situation: Researchers study, improve a small molecule that possesses an impressive ability to adhere in wet environments". ScienceDaily. Retrieved 2018-10-11.
- "Microbial Iron Uptake". labs.chem.ucsb.edu. Retrieved 2018-10-11.
- "Vanadium Haloperoxidases". labs.chem.ucsb.edu. Retrieved 2018-10-11.
- "Bio-Inspired Wet Adhesion". labs.chem.ucsb.edu. Retrieved 2018-10-11.
- Alison, Butler. "The Bioinorganic Chemistry of Iron". Grantome.
- "NSF Award Search: Award#1710761 - Bioinorganic Chemistry of Catechols: Siderophores, Adhesive Proteins and Biomimetic Analogs". www.nsf.gov. Retrieved 2018-10-11.
- Butler, Alison (1998-07-10). "Acquisition and Utilization of Transition Metal Ions by Marine Organisms" (PDF). Science. 281 (5374): 207–209. doi:10.1126/science.281.5374.207. ISSN 0036-8075. PMID 9660742.
- "Alison Butler begins term as President of SBIC". labs.chem.ucsb.edu. 2012-07-01. Retrieved 2018-10-11.
- "Alison Butler named in the 2012 Class of Fellows of the American Chemical Society". labs.chem.ucsb.edu. July 23, 2012. Retrieved 2018-10-11.
- "Alison gives the Douglas Eveleigh Endowed Lecture at the MBL sponsored by the Waksman Foundation". labs.chem.ucsb.edu. July 19, 2016. Retrieved 2018-10-11.
- "Alfred Bader Award in Bioinorganic or Bioorganic Chemistry". cen.acs.org. doi:10.1021/cen-09602-awards8. Retrieved 2018-10-11.
- "New 2019 Academy Members Announced". American Academy of Arts and Sciences. April 17, 2019.