3,4-Methylenedioxyphenylpropan-2-one

3,4-Methylenedioxyphenylpropan-2-one
Names
	IUPAC name 3,4-methylenedioxyphenylpropan-2-one[1]
	Other names 3,4-methylenedioxyphenyl-2-propanone; 1-(1,3-benzodioxol-5-yl)propan-2-one; piperonyl methyl ketone
Identifiers
CAS Number	4676-39-5 ;
3D model (JSmol)	Interactive image;
Abbreviations	MDP2P, PMK
ChemSpider	70776 ;
ECHA InfoCard	100.022.843
PubChem CID	78407;
UNII	PNA80F81BT ;
CompTox Dashboard (EPA)	DTXSID40196936 ;
	InChI InChI=1S/C10H10O3/c1-7(11)4-8-2-3-9-10(5-8)13-6-12-9/h2-3,5H,4,6H2,1H3 Key: XIYKRJLTYKUWAM-UHFFFAOYSA-N ; InChI=1/C10H10O3/c1-7(11)4-8-2-3-9-10(5-8)13-6-12-9/h2-3,5H,4,6H2,1H3 Key: XIYKRJLTYKUWAM-UHFFFAOYAA;
	SMILES O=C(C)Cc1ccc2OCOc2c1;
Properties
Chemical formula	C10H10O3
Molar mass	178.185 g/mol
Appearance	Yellowish green liquid
Density	1.211 g/cm3
Boiling point	290 °C (554 °F; 563 K)
Pharmacology
Legal status	US: List I (a precursor) ; UN: Precursors Table I ; EU: Category 1 Precursor ;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

3,4-Methylenedioxyphenylpropan-2-one[1] or piperonyl methyl ketone (MDP2P or PMK) is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. It is commonly synthesized from either safrole (which, for comparison, is 3-[3,4-(methylenedioxy)phenyl]-2-propene) or its isomer isosafrole via oxidation using the Wacker oxidation or peroxyacid oxidation methods. MDP2P is unstable at room temperature and must be kept in the freezer in order to be preserved properly.

MDP2P is a precursor in the chemical synthesis of the methylenedioxyphenethylamine (MDxx) class of compounds, the classic example of which is 3,4-methylenedioxy-N-methylamphetamine (MDMA), and is also an intermediate between the MDxx family and their slightly more distant precursor safrole or isosafrole. On account of its relation to the MDxx chemical class, MDP2P, as well as safrole and isosafrole, are in the United States (U.S.) Drug Enforcement Administration (DEA) List I of Chemicals of the Controlled Substances Act (CSA) via the Chemical Diversion and Trafficking Act (CDTA). It is also considered a category 1 precursor in the European Union.

Non-illicit Uses

MDP2P has a known use in the synthesis of Talampanel.
Podilfen [13409-53-5]
Protokylol

References

Regulation (EC) No 273/2004 of the European Parliament and of the Council of 11 February 2004 on drug precursors

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[europrecursors-1] Regulation (EC) No 273/2004 of the European Parliament and of the Council of 11 February 2004 on drug precursors

3,4-Methylenedioxyphenylpropan-2-one

See also

References