Élie Wollman
Élie Léo Wollman (July 4, 1917 – June 1, 2008) was a French microbial geneticist who first described plasmids (what he termed "episomes"), and served as vice director of research for the Pasteur Institute for twenty years.[1] He was awarded the 1976 Grand Prix Charles-Leopold Mayer by the French Academy of Sciences and Chevalier of the French Legion of Honour.[1]
Élie Wollman | |
|---|---|
| Born | July 4, 1917 Paris, France |
| Died | June 1, 2008 (aged 90) Paris, France |
| Known for | Plasmids, conjugation |
| Spouse(s) | Odile Wollman |
| Scientific career | |
| Fields | Microbial genetics |
| Institutions | Pasteur Institute |
| Thesis | Recherche sur la conjugaison des bactéries et sur le déterminisme génétique de la lysogénie [studies on bacterial conjugation and genetic determinism of lysogeny] (1958) |
Research
- In his lab at the Pasteur Institute in Paris Wollman played a key role in the elucidation of the organization of genetic material.[2]
- Developed the experimental method of interrupted mating, which underpinned the gene mapping of bacterial chromosomes.[3][4] This work laid the foundation for Francois Jacob's Nobel prize-winning work.[1]
- With Francois Jacob, he published a monograph, Sexuality and the genetics of bacteria (French title: La sexualité des bactéries), in 1959.[5]
Selected publications
- Wollman, Élie L; François Jacob (1961). Sexuality and the genetics of bacteria. New York: Academic Press.
- Wollman, E. L.; Jacob, F.; Hayes, W. (1956). "Conjugation and Genetic Recombination in Escherichia coli K-12". Cold Spring Harbor Symposia on Quantitative Biology. 21: 141–162. doi:10.1101/SQB.1956.021.01.012. PMID 13433587.
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References
- Dantzer, Robert; Keith W. Kelley (2009). "Wollman, Elie (1917–2008)". In National Academy of Sciences (U.S.) (ed.). Biographical Memoirs. Washington, D.C.: National Academies Press. ISBN 978-0-309-09579-2.
- Archives Pasteur. "Elie Wollman (1917–2008) - Notice biographique" (Biographical sketch). Archives de l'Institut Pasteur. Retrieved 2012-12-24.
- Wollman, E. L.; Jacob, F.; Hayes, W. (1956). "Conjugation and Genetic Recombination in Escherichia coli K-12". Cold Spring Harbor Symposia on Quantitative Biology. 21: 141–162. doi:10.1101/SQB.1956.021.01.012. PMID 13433587.
- Harré, Rom (2002). Great Scientific Experiments: Twenty Experiments That Changed Our View of the World. Courier Dover Publications. ISBN 978-0-486-42263-3.
- Wollman, Élie L; François Jacob (1961). Sexuality and the genetics of bacteria. New York: Academic Press.
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