You can't, basically. Not without using one of the options that require tiresome manual intervention.
"Pause Pause Pause!" stops GIF animations but is otherwise fundamentally broken -- it will, for example, get you blacklisted from Google searches due to excessive network activity or some such (I didn't debug it, but I sure got a lot of CAPTCHAs every time I tried to use Google!)
"Paused!" does not have that problem, but that seems to be largely because it doesn't actually seem to do anything at all. GIFs still animate merrily away.
This seems unlikely to change any time soon. It's already nearly two years since you asked this question, and there is still no reliable automatic solution in sight. The Chrome bug is idling because WebKit does not support the necessary features. The WebKit bug has basically not been touched since 2009. The simple fact of the matter is this: you can use Chrome, or you can stop animated GIFs automatically, but not both at once. Sorry.
It's worth mentioning that this feature would be useful because GIF heavy sites (meme sites) lag the browser. Especially on mobile. – Cole Johnson – 2014-10-02T21:38:26.120
3Actually I wish all browsers would support something like this option: stop animated gifs (and flash) by default but make it possible for the user to tell if the gif is an animated one or not, and provide a way to start the animation (or the flash) manually (maybe a clicking on the gif).
In short, stop animated gifs and flash by default but with graceful degradation.
Remote Desktop Connection users and anybody who's annoyed by seizure inducing ads would be glad to see this feature realized! – RamyenHead – 2010-03-24T06:47:37.533
This is a serious health issue for people with epilepsy. It's unacceptable that major browsers do not offer a 100% reliable bullet-proof block animation / click-to-play option for people who are vulnerable to "snow crash" attacks over twitter, etc. – Sam Watkins – 2016-12-17T12:15:56.670
You need to drop that and use Opera – random – 2011-06-17T20:06:33.037
10oh man this drives me crazy too! Why can't they support [ESC] like every other browser? – Jeff Atwood – 2009-08-31T12:36:28.617
Yeah. I'd love this to be automatic, too -- like FlashBlock. I can't think of more than five occasions where the animation actually served some (good) purpose. – Tomas Sedovic – 2009-08-31T14:45:18.677
Love uberhumor.com except for those animated GIFs posts. – Augustus Thoo – 2012-04-29T15:05:15.087