"Kind of"
For spinning rust/traditional hard drives drives there's a few elements that would determine speed.
platter size - a 2.5 inch HDD would be faster than a 3.5 inch hdd, with all other things being the same. There's a smaller 'surface area' to seek, and quite often better read speeds. This is probably more true with enterprise drives since a typical 2.5 inch drive is laptop optimised.
cache size would affect the 'burstiness' of transfer speeds. Bigger ram caches are better, and some modern drives have a huge ssd cache. This might be a critical factor since a newer drive is likely to have a bigger cache. If we has a SSHD - a hybrid with a large nand cache, you'd certainly see a difference there.
rotational speed affects seek speed and throughput, faster is faster.
More platters means greater throughput (since data can be grabbed of each of many platters) but in some cases seek times are affected, since the heads move on the same actuator.
Interfaces are important. You're probably on SATA - though 80gb and 250gb are around the the time we switched from PATA. SAS drives have somewhat more efficient encoding, wider data pipelines, and in some cases can be faster. The latest generation of drives are hung directly off the PCI bus, and are ludicrously fast. I doubt that's in the scope here tho.
In this specific case though, chances are a more modern 250gb drive would have better performance charecteristics than a 80gb drive of the same rotational speed
WIth SSDs, cache is still a factor. However number of channels and the fact that SSDs are random access storage means that all other things the same a bigger SSD typically would be faster, and split reads between nand chips.
benchmark the drives with HD tune. on their website you'll also find an extensive result browser to compare your results against other drives of the same model. – None – 2010-02-03T00:48:07.590
1At the fundamental limits, the answer is "yes". The larger the drive, for a given technology, the larger the cylinders must be, the heavier the access arm will be, etc, and hence access will be slower. (The same generalization is true for RAM.) But the effect is not usually very significant, since a given line of hard drives will tend to be designed starting with the largest, then scaling down without significant performance tuning. – Daniel R Hicks – 2015-04-29T11:30:40.587
Related finding for SSD: Why are smaller capacity SSDs slower?
– None – 2019-12-03T07:59:40.423I am not able to understand the kind of confusion of ideas that caused you to ask this question. Perhaps you can enlighten me as to why you thought this? – waiwai933 – 2009-08-30T07:55:37.660
Well I have two almost-identical hard drives; a 500GB and an 80GB. Their specs are almost exactly the same, and I recently had to install an operating system on each, and it seemed like the 80GB one was slightly faster (mainly booting up). I was just wondering if the storage capacity had anything to do with it, or whether it was something completely unrelated. – Sasha Chedygov – 2009-08-30T08:07:16.403
I had a 160 GB Seagate HD with Win 7, and then I upgraded to a Seagate 500 GB HD. The smaller hard drive was much faster than the 500 GB. I was surprised and a little disappointed. Both hard drives were brand new. I only switched them because I wanted to put the smaller one in a different computer. – None – 2014-02-02T20:24:11.653