Disclaimer: I'm plotting my first DFS implementation at work, so my understanding comes from books (specifically Windows Server 2012: Inside Out in this case) rather than practice. But, I'm definitely interested in the answer.
Assuming I understand your question, I think you're asking two discrete questions:
- How does DFS replicate?
- What determines the server that a given client connects to?
According to Windows Server 2012: Inside Out (around page 1244 or so), when a client requests a referral for a domain-based namespace, it looks a Domain Controller(herein, DC) for guidance. The DC then responds with a decision informed by data stored across several in-memory caches that describe the DFS & site structures.
First, the DC checks the referral cache for information about the requested object. If the relevant object isn't found, the DC locates the "DFS object for that namespace" to generate a referral object to pass on to the client. The referral object contains a list of UNC paths that the client can use.
The caches polled by the DC to formulate the referral object include the Site Cost cache and the Client and Target Site Caches, as well as some others. It's a little ambiguous whether the referral object also contains information gleaned from these sources so that the client can choose the best path from among the UNC paths, or if the server restricts the UNC paths returned to the client based on its assessment of 'nearness'.
Further on, it sounds like site configuration, particularly link-weights, inform the 'proximity' calculations.
Finally, I feel that manually pointing clients to specific servers would defeat one of the main reasons behind implementing DFS in the first place; i.e.: adding a layer of abstraction for clients to look up / access file shares regardless of which server said shares are located on. (Which also allows administrators to MOVE said shares when necessary, while limiting the need for reconfiguring logon scripts, etc., etc.)
PS: Sorry for the wordiness; I just got home and had to research this stuff.
EDIT: So, basically, I think what you need to do is make sure to configure a site for each... well, site that you have. IE: You probably want to create a Site for each server that's replicating over a WAN. Also, if this is a domain-based DFS implementation, you'll want to think about where your DCs are located - since the clients will be asking the nearest DC for a UNC referral.