You can also enable "Sandbox Protections".
Go to Edit > Preferences > Security (Enhanced) > Sandbox protections.
"Protected View (PV)" is a highly secure, read-only mode for Windows that blocks most actions until the user decides whether or not to trust the document. It is similar to documents opened in Microsoft Office. Users get an option to simply chose if you trust the document or not.
You can configure the feature prior to deployment manually or via the Customisation Wizard. The basic setting is:
[HKEY_CURRENT_USER\Software\Adobe\(product name)\(version)\Privileged]
"bProtectedMode"=(0|1)