Resident Evil 4/Funny

• The second special costume mode gives Ashley a full plate armor, whose helmet noisily closes as you aim at her. Have fun watching the enemies as they try to grab the girl and fall hopelessly to the ground due to her heavy armor. Or Leon himself whenever he has to catch her.
• The trophy for rescuing Ashley the first time?

"Secure the Ballistics"

• Checking the hanging meat in the kitchen during the Island Arc will prompt Leon to say he "could really use a big juicy steak right about now".
• This:

Salazar: I've sent my right hand to dispose of you.

Leon: Your right hand comes off?

• • The whole scene involving that is a nicely-layered lasagna of funny moments.

Salazar: (after dropping Leon into a death trap pit, listening into an earphone) Hmm...where is the satisfying sound of one's impalement?
Leon: (hanging from his grappling wire) I won't fall for this old trick... (aims his pistol at the other end of the earphone)
PKANG!!!

• • The best part of it all, though, is that Salazar, a Smug Snake of the highest order this whole time, flat-out flips his lid after that.
• Using the PRL-412 on the Final Boss without charging it has amusing results.