Jem/Tear Jerker

• Several episodes of Jem that focus on the Starlight girls are heartbreaking, including "The Jem Jam", with Ba Nee convinced that a stranger she's just met is her long-lost father, and the first five or so minutes of "Alone Again", with Laura Holloway depressed after her parents' deaths and sinking into loneliness and self-hatred despite Jerrica's best efforts.
• The Series Finale, with Ba Nee finding her real father at last. Jem, the Holograms, the Stingers, and the Misfits all wish her farewell via song.

Pizzazz: This is farewell to life the way we knew it...
Rio: This is farewell, but somehow we'll come through it...
Minx: We'll meet another day...

• The episodes that focus on the relationship between Jerrica and Kimber with their parents, Emmett and Jacqui Benton. Father's Day for Kimber, which focuses on the fact that Kimber has still not emotionally healed from her father's death and misses him terribly, and Out of the Past, where Jerrica remembers that she acted like a spoiled brat to her mother before she left for her next tour... and then died in the resulting plane crash.
• Riot's Hope has him trying to reconcile with his father, who doesn't approve of his being a musician, and him looking after his ailing mother.
• Video Wars, the last episode that features Clash in a speaking role, has her turn down a chance at being friends with the Holograms because she refuses to believe the Misfits aren't her friends. She tries to chase after Pizzazz and the others as they are driving away, begging for another chance to prove herself, yet Pizzazz just laughs at her as she leaves Clash standing in the dust.
• Stormer is sadly aware that all the Misfits really want to do is exploit her. They've got her warped into thinking that without them, she'd be nothing.
• The final music video for Father's Day, which the Holograms perform, provided instances of Kimber and Jerrica bonding with their deceased father, and briefly showed Harvey Gabor reflecting on one of the few moments he spent time with Pizzazz when she was a little girl.