USP36

Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. [5] [6]

USP36
Identifiers
AliasesUSP36, DUB1, ubiquitin specific peptidase 36
External IDsOMIM: 612543 MGI: 1919594 HomoloGene: 11828 GeneCards: USP36
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q25.3Start78,787,381 bp[1]
End78,841,441 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

57602

72344

Ensembl

ENSG00000055483

ENSMUSG00000033909

UniProt

Q9P275

B1AQJ2

RefSeq (mRNA)

NM_025090
NM_001321291

NM_001033528

RefSeq (protein)

NP_001308220

NP_001028700

Location (UCSC)Chr 17: 78.79 – 78.84 MbChr 11: 118.26 – 118.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000055483 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000033909 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–558. doi:10.1038/nrg1111. PMID 12838346.
  6. "Entrez Gene: USP36 ubiquitin specific peptidase 36".
  7. Endo A, Matsumoto M, Inada T, Yamamoto A, Nakayama KI, Kitamura N, Komada M (Mar 2009). "Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36". J Cell Sci. 122 (Pt 5): 678–86. doi:10.1242/jcs.044461. PMID 19208757.

Further reading


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