UBXD2

UBX domain-containing protein 4 is a protein that in humans is encoded by the UBXN4 gene.[5][6]

UBXN4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KXJ
Identifiers
Aliases	UBXN4, UBXD2, UBXDC1, erasin, UBX domain protein 4
External IDs	OMIM: 611216 MGI: 1915062 HomoloGene: 40962 GeneCards: UBXN4
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q21.3 Start 135,741,734 bp[1] End 135,785,056 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E3 Start 128,243,964 bp[2] End 128,279,378 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • nuclear envelope • endoplasmic reticulum • endoplasmic reticulum membrane • cell nucleus • membrane • cytosol Biological process • response to unfolded protein • ubiquitin-dependent ERAD pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23190	67812
Ensembl	ENSG00000144224	ENSMUSG00000026353
UniProt	Q92575	Q8VCH8
RefSeq (mRNA)	NM_014607	NM_026390 NM_001356529
RefSeq (protein)	NP_055422	NP_080666 NP_001343458
Location (UCSC)	Chr 2: 135.74 – 135.79 Mb	Chr 1: 128.24 – 128.28 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000144224 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026353 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID 16968747.
6. "Entrez Gene: UBXD2 UBX domain containing 2".

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.