TOM1L2

TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.[5][6]

TOM1L2
Identifiers
Aliases	TOM1L2, target of myb1 like 2 membrane trafficking protein
External IDs	OMIM: 615519 MGI: 2443306 HomoloGene: 44901 GeneCards: TOM1L2
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p11.2 Start 17,843,511 bp[1] End 17,972,422 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B2 Start 60,226,714 bp[2] End 60,352,905 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • clathrin binding • GO:0001948 protein binding • protein kinase binding Cellular component • extracellular exosome • intracellular • cell Biological process • protein transport • intracellular protein transport • negative regulation of mitotic nuclear division • signal transduction • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	146691	216810
Ensembl	ENSG00000175662	ENSMUSG00000000538
UniProt	Q6ZVM7	Q5SRX1
RefSeq (mRNA)	NM_001033551 NM_001082968 NM_001288786 NM_001288787 NM_001288788 NM_001288789 NM_144678 NM_001350331 NM_001350332 NM_001350333	NM_001039092 NM_001039093 NM_153080 NM_001359810
RefSeq (protein)	NP_001028723 NP_001076437 NP_001275715 NP_001275716 NP_001275717 NP_001275718 NP_001337260 NP_001337261 NP_001337262	NP_001034181 NP_001034182 NP_694720 NP_001346739
Location (UCSC)	Chr 17: 17.84 – 17.97 Mb	Chr 11: 60.23 – 60.35 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000175662 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000000538 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A (May 1999). "Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes". Genomics. 56 (1): 1–11. doi:10.1006/geno.1998.5647. PMID 10036180.
6. "Entrez Gene: TOM1L2 target of myb1-like 2 (chicken)".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Bi W, Yan J, Stankiewicz P, et al. (2002). "Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of the Mouse". Genome Res. 12 (5): 713–28. doi:10.1101/gr.73702. PMC 186594. PMID 11997338.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Katoh Y, Imakagura H, Futatsumori M, Nakayama K (2006). "Recruitment of clathrin onto endosomes by the Tom1-Tollip complex". Biochem. Biophys. Res. Commun. 341 (1): 143–9. doi:10.1016/j.bbrc.2005.12.156. PMID 16412388.
• Franco M, Furstoss O, Simon V, et al. (2006). "The Adaptor Protein Tom1L1 Is a Negative Regulator of Src Mitogenic Signaling Induced by Growth Factors". Mol. Cell. Biol. 26 (5): 1932–47. doi:10.1128/MCB.26.5.1932-1947.2006. PMC 1430241. PMID 16479011.