TC2N

Tandem C2 domains nuclear protein is a protein that in humans is encoded by the TC2N gene.[5][6]

TC2N
Identifiers
Aliases	TC2N, C14orf47, C2CD1, MTAC2D1, Tac2-N, tandem C2 domains, nuclear
External IDs	MGI: 1921663 HomoloGene: 12560 GeneCards: TC2N
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.12 Start 91,779,746 bp[1] End 91,867,536 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 E Start 101,645,443 bp[2] End 101,718,523 bp[2]
Gene ontology Molecular function • clathrin binding • calcium ion binding • syntaxin binding • molecular function • calcium-dependent phospholipid binding Cellular component • cell nucleus • cell membrane • cellular component • synapse • presynapse Biological process • vesicle fusion • calcium ion-regulated exocytosis of neurotransmitter • regulation of calcium ion-dependent exocytosis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	123036	74413
Ensembl	ENSG00000276776 ENSG00000165929	ENSMUSG00000021187
UniProt	Q8N9U0	Q91XT6
RefSeq (mRNA)	NM_152332 NM_001128595 NM_001128596 NM_001289134	NM_001082976 NM_001286364 NM_028924
RefSeq (protein)	NP_001122067 NP_001122068 NP_001276063 NP_689545	NP_001076445 NP_083200
Location (UCSC)	Chr 14: 91.78 – 91.87 Mb	Chr 12: 101.65 – 101.72 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. ENSG00000165929 GRCh38: Ensembl release 89: ENSG00000276776, ENSG00000165929 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021187 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fukuda M, Mikoshiba K (Aug 2001). "Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus". FEBS Lett. 503 (2–3): 217–218. doi:10.1016/S0014-5793(01)02738-7. PMID 11526914.
6. "Entrez Gene: MTAC2D1 membrane targeting (tandem) C2 domain containing 1".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.