TAOK2

Serine/threonine-protein kinase TAO2 is an enzyme that in humans is encoded by the TAOK2 gene.[5][6][7]

TAOK2
Identifiers
AliasesTAOK2, MAP3K17, PSK, PSK1, PSK1-BETA, TAO1, TAO2, TAO kinase 2
External IDsOMIM: 613199 MGI: 1915919 HomoloGene: 74531 GeneCards: TAOK2
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p11.2Start29,973,868 bp[1]
End29,992,261 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9344

381921

Ensembl

ENSG00000149930

ENSMUSG00000059981

UniProt

Q9UL54

Q6ZQ29

RefSeq (mRNA)

NM_001252043
NM_004783
NM_016151

NM_001163774
NM_001163775

RefSeq (protein)

NP_001238972
NP_004774
NP_057235

NP_001157246
NP_001157247

Location (UCSC)Chr 16: 29.97 – 29.99 MbChr 7: 126.87 – 126.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

TAOK2 has been shown to interact with MAP2K6[8] and MAP2K3.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000149930 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000059981 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (December 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
  6. Hutchison M, Berman KS, Cobb MH (October 1998). "Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades". The Journal of Biological Chemistry. 273 (44): 28625–32. doi:10.1074/jbc.273.44.28625. PMID 9786855.
  7. "Entrez Gene: TAOK2 TAO kinase 2".
  8. Chen Z, Cobb MH (May 2001). "Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2". The Journal of Biological Chemistry. 276 (19): 16070–5. doi:10.1074/jbc.M100681200. PMID 11279118.

Further reading

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