Sorin Draghici

Sorin Drăghici is a Romanian-American computer scientist, the Associate Dean for Entrepreneurship and Innovation of Wayne State University's College of Engineering, and the Director of the James and Patricia Anderson Engineering Ventures Institute.[1][2]

Sorin Drăghici
CitizenshipUnited States
Alma materUniversity of St Andrews, UK
Scientific career
FieldsComputer Science, Bioinformatics, Computational biology, Machine learning, Neural networks, and Biomedical Informatics
InstitutionsWayne State University
Doctoral advisorMichael K. Weir

Biography

Draghici was born and raised in Bucharest, Romania. He studied computer engineering at the Politehnica University of Bucharest from where he obtained an M.Sc. He completed a Ph.D. in Computer Science at the University of St Andrews, UK in the area of deep learning/neural networks. He joined the Computer Science Department at Wayne State University in 1996.

Current position

Draghici is a Professor in the Department of Computer Science College of Engineering and Obstetrics and Gynecology in the School of Medicine. He is also the current holder of the Robert J. Sokol Endowed Chair in Systems Biology in Reproduction and a member of the Board of Directors for TechTown, Wayne State University's research park and business incubator.[3] Draghici is also the founder and CEO of AdvaitaBio.

Research

His research area is computational biology and bioinformatics, in particular GO analysis,[4][5] pathway analysis,[6][7][8][9][10][11] meta-analysis,[12][13][14][15][16][17] and drug repurposing.[18][19] His research has been supported by the National Science Foundation,[20] National Health Institutes [21][22][23][24][25][26] and others. He has published over 190 scholarly papers [27][28] and two technical books: Statistics and Data Analysis for Microarrays Using R and Bioconductor and Data Analysis Tools for DNA Microarrays.

He is an editor for IEEE/ACM Transactions on Computational Biology and Bioinformatics,[29] Current Protocols in Bioinformatics,[30] Journal of Biomedicine and Biotechnology,[31] and a senior editor of the Discoveries Journal.[32]

References
  1. "Anderson Institute - Entrepreneurship and the Anderson Institute - Wayne State University".
  2. "Entrepreneurship and the Anderson Institute - Wayne State University".
  3. "TechTown Detroit names two new board members".
  4. Khatri, Purvesh; Draghici, Sorin; Ostermeier, G.Charles; Krawetz, Stephen A. (February 2002). "Profiling Gene Expression Using Onto-Express". Genomics. 79 (2): 266–270. doi:10.1006/geno.2002.6698.
  5. Drǎghici, Sorin; Khatri, Purvesh; Martins, Rui P.; Ostermeier, G.Charles; Krawetz, Stephen A. (February 2003). "Global functional profiling of gene expression☆☆This work was funded in part by a Sun Microsystems grant awarded to S.D., NIH Grant HD36512 to S.A.K., a Wayne State University SOM Dean's Post-Doctoral Fellowship, and an NICHD Contraception and Infertility Loan to G.C.O. Support from the WSU MCBI mode is gratefully appreciated". Genomics. 81 (2): 98–104. doi:10.1016/S0888-7543(02)00021-6.
  6. Draghici, S.; Khatri, P.; Tarca, A. L.; Amin, K.; Done, A.; Voichita, C.; Georgescu, C.; Romero, R. (2007-09-04). "A systems biology approach for pathway level analysis". Genome Research. 17 (10): 1537–1545. doi:10.1101/gr.6202607. ISSN 1088-9051. PMC 1987343. PMID 17785539.
  7. Donato, Michele; Xu, Zhonghui; Tomoiaga, Alin; Granneman, James G.; MacKenzie, Robert G.; Bao, Riyue; Than, Nandor Gabor; Westfall, Peter H.; Romero, Roberto; Draghici, Sorin (November 2013). "Analysis and correction of crosstalk effects in pathway analysis". Genome Research. 23 (11): 1885–1893. doi:10.1101/gr.153551.112. ISSN 1088-9051. PMC 3814888. PMID 23934932.
  8. Tarca, Adi Laurentiu; Draghici, Sorin; Bhatti, Gaurav; Romero, Roberto (December 2012). "Down-weighting overlapping genes improves gene set analysis". BMC Bioinformatics. 13 (1): 136. doi:10.1186/1471-2105-13-136. ISSN 1471-2105. PMC 3443069. PMID 22713124.
  9. Hanoudi, Samer; Donato, Michele; Draghici, Sorin (2017-05-09). Escriva, Hector (ed.). "Identifying biologically relevant putative mechanisms in a given phenotype comparison". PLOS ONE. 12 (5): e0176950. doi:10.1371/journal.pone.0176950. ISSN 1932-6203. PMC 5423614. PMID 28486531.
  10. Hanoudi, Samer; Donato, Michele; Draghici, Sorin (2017-05-09). Escriva, Hector (ed.). "Identifying biologically relevant putative mechanisms in a given phenotype comparison". PLOS ONE. 12 (5): e0176950. doi:10.1371/journal.pone.0176950. ISSN 1932-6203. PMC 5423614. PMID 28486531.
  11. Nguyen, Tuan-Minh; Shafi, Adib; Nguyen, Tin; Draghici, Sorin (December 2019). "Identifying significantly impacted pathways: a comprehensive review and assessment". Genome Biology. 20 (1): 203. doi:10.1186/s13059-019-1790-4. ISSN 1474-760X. PMC 6784345. PMID 31597578.
  12. Nguyen, Tin; Tagett, Rebecca; Donato, Michele; Mitrea, Cristina; Draghici, Sorin (2016-02-01). "A novel bi-level meta-analysis approach: applied to biological pathway analysis". Bioinformatics. 32 (3): 409–416. doi:10.1093/bioinformatics/btv588. ISSN 1367-4803. PMC 5006307. PMID 26471455.
  13. Nguyen, Tin; Diaz, Diana; Draghici, Sorin (2016-10-02). "TOMAS: A novel TOpology-aware Meta-Analysis approach applied to System biology". Proceedings of the 7th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics. Seattle WA USA: ACM: 13–22. doi:10.1145/2975167.2975168. ISBN 978-1-4503-4225-4.
  14. Nguyen, Tin; Mitrea, Cristina; Tagett, Rebecca; Draghici, Sorin (March 2017). "DANUBE: Data-Driven Meta-ANalysis Using UnBiased Empirical Distributions—Applied to Biological Pathway Analysis". Proceedings of the IEEE. 105 (3): 496–515. doi:10.1109/JPROC.2015.2507119. ISSN 0018-9219.
  15. Shafi, Adib; Nguyen, Tin; Peyvandipour, Azam; Draghici, Sorin (2019-07-22). Kelso, Janet (ed.). "GSMA: an approach to identify robust global and test Gene Signatures using Meta-Analysis". Bioinformatics: btz561. doi:10.1093/bioinformatics/btz561. ISSN 1367-4803.
  16. Shafi, Adib; Nguyen, Tin; Peyvandipour, Azam; Nguyen, Hung; Draghici, Sorin (2019-03-19). "A Multi-Cohort and Multi-Omics Meta-Analysis Framework to Identify Network-Based Gene Signatures". Frontiers in Genetics. 10: 159. doi:10.3389/fgene.2019.00159. ISSN 1664-8021. PMC 6434849. PMID 30941158.
  17. Nguyen, Tin; Shafi, Adib; Nguyen, Tuan-Minh; Schissler, A. Grant; Draghici, Sorin (December 2020). "NBIA: a network-based integrative analysis framework – applied to pathway analysis". Scientific Reports. 10 (1): 4188. doi:10.1038/s41598-020-60981-9. ISSN 2045-2322. PMC 7060280. PMID 32144346.
  18. Saberian, Nafiseh; Peyvandipour, Azam; Donato, Michele; Ansari, Sahar; Draghici, Sorin (2019-10-01). Kelso, Janet (ed.). "A new computational drug repurposing method using established disease–drug pair knowledge". Bioinformatics. 35 (19): 3672–3678. doi:10.1093/bioinformatics/btz156. ISSN 1367-4803. PMC 6761937. PMID 30840053.
  19. Peyvandipour, Azam; Saberian, Nafiseh; Shafi, Adib; Donato, Michele; Draghici, Sorin (2018-08-15). Valencia, Alfonso (ed.). "A novel computational approach for drug repurposing using systems biology". Bioinformatics. 34 (16): 2817–2825. doi:10.1093/bioinformatics/bty133. ISSN 1367-4803. PMC 6084573. PMID 29534151.
  20. "NSF Award Search: Simple Search Results".
  21. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  22. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  23. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  24. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  25. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  26. "Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results".
  27. "Google Scholar". Google Scholar. Retrieved 29 November 2016.
  28. http://orcid.org/0000-0002-0786-8377
  29. "About TCBB • IEEE Computer Society".
  30. Baxevanis, Andreas D. (2002). Bateman, Alex; Pearson, William R; Stein, Lincoln D; Stormo, Gary D; Yates, John R (eds.). Current Protocols in Bioinformatics. CiteSeerX 10.1.1.419.8061. doi:10.1002/0471250953. ISBN 9780471250951.
  31. "BioMed Research International: Bioinformatics".
  32. "Editorial Board of DISCOVERIES and DISCOVERIES REPORTS".
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