Sialic acid binding ig-like lectin 15

Sialic acid binding Ig-like lectin 15 is a protein that in humans is encoded by the SIGLEC15 gene.[5]

SIGLEC15
Identifiers
Aliases	SIGLEC15, CD33L3, HsT1361, SIGLEC-15, Sialic acid binding ig-like lectin 15, sialic acid binding Ig like lectin 15
External IDs	OMIM: 618105 MGI: 3646642 HomoloGene: 52643 GeneCards: SIGLEC15
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q12.3 Start 45,825,675 bp[1] End 45,844,094 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 E3 Start 78,043,614 bp[2] End 78,057,395 bp[2]
Orthologs
Species	Human	Mouse
Entrez	284266	620235
Ensembl	ENSG00000197046	ENSMUSG00000091055
UniProt	Q6ZMC9	A7E1W8
RefSeq (mRNA)	NM_213602	NM_001101038
RefSeq (protein)	NP_998767	NP_001094508
Location (UCSC)	Chr 18: 45.83 – 45.84 Mb	Chr 18: 78.04 – 78.06 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000197046 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000091055 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Sialic acid binding Ig-like lectin 15".

Further reading

• Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T (February 2013). "The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway". Glycobiology. 23 (2): 178–87. doi:10.1093/glycob/cws139. PMID 23035012.
• Angata T, Tabuchi Y, Nakamura K, Nakamura M (August 2007). "Siglec-15: an immune system Siglec conserved throughout vertebrate evolution". Glycobiology. 17 (8): 838–46. doi:10.1093/glycob/cwm049. PMID 17483134.