Saflufenacil
Saflufenacil is an herbicide of the pyrimidinedione chemical class used to control annual broadleaf weeds in soybeans and corn. It was developed by BASF and is marketed under the Kixor trademark.[2]
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| Names | |
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| IUPAC name
N′-{2-Chloro-4-fluoro-5-[1,2,3,6-tetrahydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzoyl}-N-isopropyl-N-methylsulfamide | |
| Systematic IUPAC name
2-Chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.124.700 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties[1] | |
| C17H17ClF4N4O5S | |
| Molar mass | 500.85 g·mol−1 |
| Density | 1.595 g/mL |
| Melting point | 189.9 °C (373.8 °F; 463.0 K) |
| 2100 mg/L (20 °C) | |
| Hazards | |
| R-phrases (outdated) | R63-R22-R50-R53 |
| S-phrases (outdated) | (S1/2)-S13-S26-S36/37/39-S46 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Saflufenacil works by inhibiting protoporphyrinogen IX oxidase (PPO), resulting in plant accumulation of protoporphyrin IX (proto) and H2O2; inhibiting PPO formation results in prevention of chlorophyll, heme, and cytochrome synthesis; also, proto accumulation causes lipid peroxidation, resulting in rapid loss of membrane integrity and function; only slight increases of proto and H2O2 occur in corn.[3]
References
- Saflufenacil in the Pesticide Properties DataBase (PPDB)
- "Kixor Herbicide Broadleaf Weed Control". BASF.
- Grossman, K., et. al., The Herbicide Saflufenacil (KixorTM) is a New Inhibitor of Protoporphyrinogen IX Oxidase Activity, Weed Science, 58, pp. 1-9, 2010
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