SYNPR

Synaptoporin is a protein that in humans is encoded by the SYNPR gene.[5][6][7]

SYNPR
Identifiers
Aliases	SYNPR, SPO, synaptoporin
External IDs	MGI: 1919253 HomoloGene: 11407 GeneCards: SYNPR
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p14.2 Start 63,228,315 bp[1] End 63,616,924 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A1 Start 13,284,780 bp[2] End 13,616,340 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • syntaxin-1 binding Cellular component • synapse • membrane • cell junction • cytoplasmic vesicle • integral component of synaptic vesicle membrane • synaptic vesicle membrane • neuron projection • integral component of membrane • synaptic vesicle Biological process • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	132204	72003
Ensembl	ENSG00000163630	ENSMUSG00000056296
UniProt	Q8TBG9	Q8BGN8
RefSeq (mRNA)	NM_001130003 NM_144642	NM_001163032 NM_028052
RefSeq (protein)	NP_001123475 NP_653243	NP_001156504 NP_082328
Location (UCSC)	Chr 3: 63.23 – 63.62 Mb	Chr 14: 13.28 – 13.62 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163630 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000056296 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Leube RE (Aug 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.
6. Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (Sep 2003). "Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein". Mol Biol Rep. 30 (3): 185–91. doi:10.1023/A:1024907723000. PMID 12974474.
7. "Entrez Gene: SYNPR synaptoporin".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Singec I, Knoth R, Ditter M, et al. (2002). "Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons". J. Comp. Neurol. 452 (2): 139–53. doi:10.1002/cne.10371. PMID 12271488.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tran MH, Yamada K, Nakajima A, et al. (2004). "Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction". Mol. Psychiatry. 8 (4): 407–12. doi:10.1038/sj.mp.4001240. PMID 12740598.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.