STRBP

Spermatid perinuclear RNA-binding protein is a protein that in humans is encoded by the STRBP gene.[5]

STRBP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DMY
Identifiers
Aliases	STRBP, HEL162, ILF3L, SPNR, p74, spermatid perinuclear RNA binding protein
External IDs	OMIM: 611138 MGI: 104626 HomoloGene: 7548 GeneCards: STRBP
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.3 Start 123,109,500 bp[1] End 123,268,586 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 37,483,228 bp[2] End 37,703,859 bp[2]
Gene ontology Molecular function • DNA binding • double-stranded RNA binding • GO:0001948 protein binding • single-stranded RNA binding • RNA binding • microtubule binding • tubulin binding Cellular component • cytoplasm • microtubule cytoskeleton • cell nucleus • manchette Biological process • multicellular organism development • mechanosensory behavior • cell differentiation • spermatogenesis • spermatid development Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55342	20744
Ensembl	ENSG00000165209	ENSMUSG00000026915
UniProt	Q96SI9	Q91WM1
RefSeq (mRNA)	NM_001171137 NM_018387 NM_001376106 NM_001376107 NM_001376109	NM_009261 NM_176932 NM_001355259 NM_001355260 NM_001379314 NM_001379315 NM_001379316
RefSeq (protein)	NP_001164608 NP_060857 NP_001363035 NP_001363036 NP_001363038	NP_033287 NP_001342188 NP_001342189 NP_001366243 NP_001366244 NP_001366245
Location (UCSC)	Chr 9: 123.11 – 123.27 Mb	Chr 2: 37.48 – 37.7 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000165209 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026915 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".

Further reading

• Schumacher JM, Lee K, Edelhoff S, Braun RE (May 1995). "Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules". The Journal of Cell Biology. 129 (4): 1023–32. doi:10.1083/jcb.129.4.1023. PMC 2120489. PMID 7744952.
• Schumacher JM, Artzt K, Braun RE (July 1998). "Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice". Biology of Reproduction. 59 (1): 69–76. doi:10.1095/biolreprod59.1.69. PMID 9674995.
• Coolidge CJ, Patton JG (March 2000). "A new double-stranded RNA-binding protein that interacts with PKR". Nucleic Acids Research. 28 (6): 1407–17. doi:10.1093/nar/28.6.1407. PMC 111047. PMID 10684936.
• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P (May 2001). "Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities" (PDF). Developmental Biology. 233 (2): 319–28. doi:10.1006/dbio.2001.0169. PMID 11336498.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.