Monocarboxylate transporter 10

Monocarboxylate transporter 10 (MCT 10), also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene.[5][6][7] SLC16A10 is a member of the solute carrier family.

SLC16A10
Identifiers
AliasesSLC16A10, MCT10, PRO0813, TAT1, solute carrier family 16 member 10
External IDsOMIM: 607550 MGI: 1919722 HomoloGene: 75089 GeneCards: SLC16A10
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6q21Start111,087,503 bp[1]
End111,231,194 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

117247

72472

Ensembl

ENSG00000112394

ENSMUSG00000019838

UniProt

Q8TF71

Q3U9N9

RefSeq (mRNA)

NM_018593

NM_001114332
NM_028247

RefSeq (protein)

NP_061063

NP_001107804
NP_082523

Location (UCSC)Chr 6: 111.09 – 111.23 MbChr 10: 40.03 – 40.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

SLC16A10 mediates Na+-independent transport of tryptophan, tyrosine, phenylalanine, and L-DOPA.[7]

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See also

References

  1. GRCh38: Ensembl release 89: ENSG00000112394 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000019838 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: solute carrier family 16".
  6. Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H (May 2001). "Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters". J. Biol. Chem. 276 (20): 17221–8. doi:10.1074/jbc.M009462200. PMID 11278508.
  7. Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H (January 2002). "The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location". Genomics. 79 (1): 95–103. doi:10.1006/geno.2001.6678. PMID 11827462.

Further reading


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