RTRAF

RNA transcription, translation and transport factor is a protein that in humans is encoded by the RTRAF gene.[5][6]

RTRAF
Identifiers
Aliases	RTRAF, CGI99, CLE, CLE7, LCRP369, RLLM1, CGI-99, C14orf166, hCLE1, chromosome 14 open reading frame 166, RNA transcription, translation and transport factor, hCLE
External IDs	OMIM: 610858 MGI: 1915295 HomoloGene: 9355 GeneCards: RTRAF
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q22.1 Start 51,989,514 bp[1] End 52,010,694 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 A3 Start 19,811,351 bp[2] End 19,823,824 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • RNA polymerase II core binding • identical protein binding • RNA binding • GO:0001948 protein binding Cellular component • cytoskeleton • cytosol • cell nucleus • tRNA-splicing ligase complex • cytoplasm • microtubule organizing center • nucleoplasm • centrosome • perinuclear region of cytoplasm • mitotic spindle Biological process • RNA transport • regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • GO:0022415 viral process • tRNA splicing, via endonucleolytic cleavage and ligation • negative regulation of protein kinase activity Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51637	68045
Ensembl	ENSG00000087302	ENSMUSG00000021807
UniProt	Q9Y224	Q9CQE8
RefSeq (mRNA)	NM_016039	NM_026528
RefSeq (protein)	NP_057123	NP_080804
Location (UCSC)	Chr 14: 51.99 – 52.01 Mb	Chr 14: 19.81 – 19.82 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000087302 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021807 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]". Retrieved 2019-04-28.

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Howng SL, Hsu HC, Cheng TS, et al. (2004). "A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors". FEBS Lett. 566 (1–3): 162–8. doi:10.1016/j.febslet.2004.04.024. PMID 15147888.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Huarte M, Sanz-Ezquerro JJ, Roncal F, et al. (2001). "PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators". J. Virol. 75 (18): 8597–604. doi:10.1128/JVI.75.18.8597-8604.2001. PMC 115105. PMID 11507205.
• Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.