RPAIN

RPA-interacting protein is a protein that in humans is encoded by the RPAIN gene.[5][6][7]

RPAIN
Identifiers
Aliases	RPAIN, HRIP, RIP, RPA interacting protein
External IDs	OMIM: 617299 MGI: 1916973 HomoloGene: 13006 GeneCards: RPAIN
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.2 Start 5,419,641 bp[1] End 5,432,876 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B4 Start 70,970,213 bp[2] End 70,977,833 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding • GO:0032403 macromolecular complex binding Cellular component • cytoplasm • PML body • cell nucleus • fibrillar center Biological process • DNA-dependent DNA replication • DNA recombination • response to UV • DNA repair • protein import into nucleus Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84268	69723
Ensembl	ENSG00000129197	ENSMUSG00000018449
UniProt	Q86UA6	Q9CWY9
RefSeq (mRNA)	NM_001033002 NM_001160243 NM_001160244 NM_001160246 NM_001160266 NM_001160267 NM_032308	NM_001252413 NM_001252414 NM_001252415 NM_027186
RefSeq (protein)	NP_001028174 NP_001153715 NP_001153716 NP_001153718 NP_001153738	NP_001239342 NP_001239343 NP_001239344 NP_081462
Location (UCSC)	Chr 17: 5.42 – 5.43 Mb	Chr 11: 70.97 – 70.98 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000129197 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018449 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Park J, Seo T, Kim H, Choe J (Sep 2005). "Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies". Mol Cell Biol. 25 (18): 8202–14. doi:10.1128/MCB.25.18.8202-8214.2005. PMC 1234305. PMID 16135809.
6. Chen JZ, Huang SD, Ji CN, Pang RY, Xie Y, Xue JL (Jul 2005). "Identification, expression pattern, and subcellular location of human RIP isoforms". DNA Cell Biol. 24 (7): 464–9. doi:10.1089/dna.2005.24.464. PMID 16008515.
7. "Entrez Gene: RPAIN RPA interacting protein".

Further reading

• Blonska M, You Y, Geleziunas R, Lin X (2004). "Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells". Mol. Cell. Biol. 24 (24): 10757–65. doi:10.1128/MCB.24.24.10757-10765.2004. PMC 533972. PMID 15572679.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.