RETNLB

Resistin-like beta is a protein that in humans is encoded by the RETNLB gene.[5][6][7]

RETNLB
Identifiers
Aliases	RETNLB, FIZZ1, FIZZ2, HXCP2, RELM-beta, RELMb, RELMbeta, XCP2, resistin like beta
External IDs	OMIM: 605645 MGI: 1888505 HomoloGene: 10735 GeneCards: RETNLB
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.13 Start 108,743,424 bp[1] End 108,757,384 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16 B5|16 30.75 cM Start 48,816,856 bp[2] End 48,818,892 bp[2]
Gene ontology Molecular function • hormone activity • molecular function Cellular component • extracellular region • extracellular • cellular component Biological process • cellular proliferation • regulation of receptor activity • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84666	57263
Ensembl	ENSG00000163515	ENSMUSG00000022650
UniProt	Q9BQ08	Q99P86
RefSeq (mRNA)	NM_032579	NM_023881
RefSeq (protein)	NP_115968	NP_076370
Location (UCSC)	Chr 3: 108.74 – 108.76 Mb	Chr 16: 48.82 – 48.82 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163515 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022650 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Holcomb IN, Kabakoff RC, Chan B, Baker TW, Gurney A, Henzel W, Nelson C, Lowman HB, Wright BD, Skelton NJ, Frantz GD, Tumas DB, Peale FV Jr, Shelton DL, Hebert CC (Sep 2000). "FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family". EMBO J. 19 (15): 4046–55. doi:10.1093/emboj/19.15.4046. PMC 306596. PMID 10921885.
6. Stutz AM, Pickart LA, Trifilieff A, Baumruker T, Prieschl-Strassmayr E, Woisetschlager M (Feb 2003). "The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism". J Immunol. 170 (4): 1789–96. doi:10.4049/jimmunol.170.4.1789. PMID 12574343.
7. "Entrez Gene: RETNLB resistin like beta".

Further reading

• Kubota T, Kawano S, Chih DY, et al. (2001). "Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice". Blood. 96 (12): 3953–7. PMID 11090083.
• Steppan CM, Brown EJ, Wright CM, et al. (2001). "A family of tissue-specific resistin-like molecules". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 502–6. doi:10.1073/pnas.98.2.502. PMC 14616. PMID 11209052.
• De Young MP, Damania H, Scheurle D, et al. (2003). "Bioinformatics-based discovery of a novel factor with apparent specificity to colon cancer". In Vivo. 16 (4): 239–48. PMID 12224133.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• He W, Wang ML, Jiang HQ, et al. (2003). "Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein". Gastroenterology. 125 (5): 1388–97. doi:10.1016/j.gastro.2003.07.009. PMID 14598255.
• Chumakov AM, Kubota T, Walter S, Koeffler HP (2004). "Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family". Oncogene. 23 (19): 3414–25. doi:10.1038/sj.onc.1207126. PMID 15064728.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Renigunta A, Hild C, Rose F, et al. (2006). "Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia". FEBS Lett. 580 (3): 900–3. doi:10.1016/j.febslet.2006.01.012. PMID 16427636.