RERG

RAS-like, estrogen-regulated, growth inhibitor is a protein in humans that is encoded by the RERG gene. [5]

RERG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ATV
Identifiers
Aliases	RERG, RAS like estrogen regulated growth inhibitor
External IDs	OMIM: 612664 MGI: 2665139 HomoloGene: 50026 GeneCards: RERG
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p12.3 Start 15,107,783 bp[1] End 15,348,675 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 G1 Start 137,054,825 bp[2] End 137,170,497 bp[2]
Gene ontology Molecular function • nucleotide binding • GTP binding • GDP binding • estrogen receptor binding • GTPase activity Cellular component • cytosol • cell nucleus • membrane • cytoplasm • cell membrane Biological process • negative regulation of cell proliferation • response to hormone • negative regulation of cell growth • signal transduction • small GTPase mediated signal transduction • Ras protein signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	85004	232441
Ensembl	ENSG00000134533	ENSMUSG00000030222
UniProt	Q96A58	Q8R367
RefSeq (mRNA)	NM_001190726 NM_032918	NM_001164212 NM_001164214 NM_181988
RefSeq (protein)	NP_001177655 NP_116307	NP_001157684 NP_001157686 NP_871788
Location (UCSC)	Chr 12: 15.11 – 15.35 Mb	Chr 6: 137.05 – 137.17 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009].

References

1. GRCh38: Ensembl release 89: ENSG00000134533 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030222 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RAS-like, estrogen-regulated, growth inhibitor". Retrieved 2012-11-09.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Ras-related and estrogen-regulated growth inhibitor (RERG)

Further reading