RAB3IP

RAB3A-interacting protein is a protein that in humans is encoded by the RAB3IP gene.[5]

RAB3IP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4LHX, 4LHY, 4LHZ, 4UJ3, 4UJ4, 4UJ5
Identifiers
Aliases	RAB3IP, RABIN3, RABIN8, RAB3A interacting protein
External IDs	OMIM: 608686 MGI: 105933 HomoloGene: 32340 GeneCards: RAB3IP
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q15 Start 69,738,681 bp[1] End 69,823,204 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D2|10 64.96 cM Start 116,905,784 bp[2] End 116,950,769 bp[2]
Gene ontology Molecular function • Rab guanyl-nucleotide exchange factor activity • GO:0001948 protein binding • guanyl-nucleotide exchange factor activity • identical protein binding Cellular component • cytoplasm • ciliary basal body • cytosol • centrosome • cell projection • cytoskeleton • lamellipodium • cell nucleus Biological process • protein localization to organelle • protein transport • Golgi to plasma membrane transport • protein targeting to membrane • cilium morphogenesis • ciliary basal body docking Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	117177	216363
Ensembl	ENSG00000127328	ENSMUSG00000064181
UniProt	Q96QF0	Q68EF0
RefSeq (mRNA)	NM_001024647 NM_001278402 NM_022456 NM_175623 NM_175624 NM_175625 NM_175626 NM_175627	NM_001003950 NM_001359645
RefSeq (protein)	NP_001019818 NP_001265331 NP_071901 NP_783322 NP_783323 NP_783324	NP_001003950 NP_001346574
Location (UCSC)	Chr 12: 69.74 – 69.82 Mb	Chr 10: 116.91 – 116.95 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000127328 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000064181 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RAB3IP RAB3A interacting protein (rabin3)".

Further reading

• Newport J, Roemer MI (1975). "Comparative perinatal mortality under medical care foundations and other delivery models". Inquiry : a journal of medical care organization, provision and financing. 12 (1): 10–7. PMID 123217.
• Brondyk WH, McKiernan CJ, Fortner KA, et al. (1995). "Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A". Mol. Cell. Biol. 15 (3): 1137–43. doi:10.1128/MCB.15.3.1137. PMC 230335. PMID 7532276.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• de Bruijn DR, dos Santos NR, Kater-Baats E, et al. (2002). "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP". Genes Chromosomes Cancer. 34 (3): 285–98. doi:10.1002/gcc.10073. PMID 12007189.
• Hattula K, Furuhjelm J, Arffman A, Peränen J (2003). "A Rab8-specific GDP/GTP Exchange Factor Is Involved in Actin Remodeling and Polarized Membrane Transport". Mol. Biol. Cell. 13 (9): 3268–80. doi:10.1091/mbc.E02-03-0143. PMC 124888. PMID 12221131.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• Overview of all the structural information available in the PDB for UniProt: Q96QF0 (Rab-3A-interacting protein) at the PDBe-KB.